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Magic™ Membrane Protein Human CELSR2 (Cadherin EGF LAG seven-pass G-type receptor 2) Full Length (CAT#: MPC0060K) Made to Order

Datasheet
This product is a 317.4 kDa Human CELSR2 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • CELSR2
  • Protein Length
  • Full length
  • Protein Class
  • GPCR
  • Molecular Weight
  • 317.4 kDa
  • TMD
  • 7
  • Sequence
  • MRSPATGVPLPTPPPPLLLLLLLLLPPPLLGDQVGPCRSLGSRGRGSSGA
    CAPMGWLCPSSASNLWLYTSRCRDAGTELTGHLVPHHDGLRVWCPESEAH
    IPLPPAPEGCPWSCRLLGIGGHLSPQGKLTLPEEHPCLKAPRLRCQSCKL
    AQAPGLRAGERSPEESLGGRRKRNVNTAPQFQPPSYQATVPENQPAGTPV
    ASLRAIDPDEGEAGRLEYTMDALFDSRSNQFFSLDPVTGAVTTAEELDRE
    TKSTHVFRVTAQDHGMPRRSALATLTILVTDTNDHDPVFEQQEYKESLRE
    NLEVGYEVLTVRATDGDAPPNANILYRLLEGSGGSPSEVFEIDPRSGVIR
    TRGPVDREEVESYQLTVEASDQGRDPGPRSTTAAVFLSVEDDNDNAPQFS
    EKRYVVQVREDVTPGAPVLRVTASDRDKGSNAVVHYSIMSGNARGQFYLD
    AQTGALDVVSPLDYETTKEYTLRVRAQDGGRPPLSNVSGLVTVQVLDIND
    NAPIFVSTPFQATVLESVPLGYLVLHVQAIDADAGDNARLEYRLAGVGHD
    FPFTINNGTGWISVAAELDREEVDFYSFGVEARDHGTPALTASASVSVTV
    LDVNDNNPTFTQPEYTVRLNEDAAVGTSVVTVSAVDRDAHSVITYQITSG
    NTRNRFSITSQSGGGLVSLALPLDYKLERQYVLAVTASDGTRQDTAQIVV
    NVTDANTHRPVFQSSHYTVNVNEDRPAGTTVVLISATDEDTGENARITYF
    MEDSIPQFRIDADTGAVTTQAELDYEDQVSYTLAITARDNGIPQKSDTTY
    LEILVNDVNDNAPQFLRDSYQGSVYEDVPPFTSVLQISATDRDSGLNGRV
    FYTFQGGDDGDGDFIVESTSGIVRTLRRLDRENVAQYVLRAYAVDKGMPP
    ARTPMEVTVTVLDVNDNPPVFEQDEFDVFVEENSPIGLAVARVTATDPDE
    GTNAQIMYQIVEGNIPEVFQLDIFSGELTALVDLDYEDRPEYVLVIQATS
    APLVSRATVHVRLLDRNDNPPVLGNFEILFNNYVTNRSSSFPGGAIGRVP
    AHDPDISDSLTYSFERGNELSLVLLNASTGELKLSRALDNNRPLEAIMSV
    LVSDGVHSVTAQCALRVTIITDEMLTHSITLRLEDMSPERFLSPLLGLFI
    QAVAATLATPPDHVVVFNVQRDTDAPGGHILNVSLSVGQPPGPGGGPPFL
    PSEDLQERLYLNRSLLTAISAQRVLPFDDNICLREPCENYMRCVSVLRFD
    SSAPFIASSSVLFRPIHPVGGLRCRCPPGFTGDYCETEVDLCYSRPCGPH
    GRCRSREGGYTCLCRDGYTGEHCEVSARSGRCTPGVCKNGGTCVNLLVGG
    FKCDCPSGDFEKPYCQVTTRSFPAHSFITFRGLRQRFHFTLALSFATKER
    DGLLLYNGRFNEKHDFVALEVIQEQVQLTFSAGESTTTVSPFVPGGVSDG
    QWHTVQLKYYNKPLLGQTGLPQGPSEQKVAVVTVDGCDTGVALRFGSVLG
    NYSCAAQGTQGGSKKSLDLTGPLLLGGVPDLPESFPVRMRQFVGCMRNLQ
    VDSRHIDMADFIANNGTVPGCPAKKNVCDSNTCHNGGTCVNQWDAFSCEC
    PLGFGGKSCAQEMANPQHFLGSSLVAWHGLSLPISQPWYLSLMFRTRQAD
    GVLLQAITRGRSTITLQLREGHVMLSVEGTGLQASSLRLEPGRANDGDWH
    HAQLALGASGGPGHAILSFDYGQQRAEGNLGPRLHGLHLSNITVGGIPGP
    AGGVARGFRGCLQGVRVSDTPEGVNSLDPSHGESINVEQGCSLPDPCDSN
    PCPANSYCSNDWDSYSCSCDPGYYGDNCTNVCDLNPCEHQSVCTRKPSAP
    HGYTCECPPNYLGPYCETRIDQPCPRGWWGHPTCGPCNCDVSKGFDPDCN
    KTSGECHCKENHYRPPGSPTCLLCDCYPTGSLSRVCDPEDGQCPCKPGVI
    GRQCDRCDNPFAEVTTNGCEVNYDSCPRAIEAGIWWPRTRFGLPAAAPCP
    KGSFGTAVRHCDEHRGWLPPNLFNCTSITFSELKGFAERLQRNESGLDSG
    RSQQLALLLRNATQHTAGYFGSDVKVAYQLATRLLAHESTQRGFGLSATQ
    DVHFTENLLRVGSALLDTANKRHWELIQQTEGGTAWLLQHYEAYASALAQ
    NMRHTYLSPFTIVTPNIVISVVRLDKGNFAGAKLPRYEALRGEQPPDLET
    TVILPESVFRETPPVVRPAGPGEAQEPEELARRQRRHPELSQGEAVASVI
    IYRTLAGLLPHNYDPDKRSLRVPKRPIINTPVVSISVHDDEELLPRALDK
    PVTVQFRLLETEERTKPICVFWNHSILVSGTGGWSARGCEVVFRNESHVS
    CQCNHMTSFAVLMDVSRRENGEILPLKTLTYVALGVTLAALLLTFFFLTL
    LRILRSNQHGIRRNLTAALGLAQLVFLLGINQADLPFACTVIAILLHFLY
    LCTFSWALLEALHLYRALTEVRDVNTGPMRFYYMLGWGVPAFITGLAVGL
    DPEGYGNPDFCWLSIYDTLIWSFAGPVAFAVSMSVFLYILAARASCAAQR
    QGFEKKGPVSGLQPSFAVLLLLSATWLLALLSVNSDTLLFHYLFATCNCI
    QGPFIFLSYVVLSKEVRKALKLACSRKPSPDPALTTKSTLTSSYNCPSPY
    ADGRLYQPYGDSAGSLHSTSRSGKSQPSYIPFLLREESALNPGQGPPGLG
    DPGSLFLEGQDQQHDPDTDSDSDLSLEDDQSGSYASTHSSDSEEEEEEEE
    EEAAFPGEQGWDSLLGPGAERLPLHSTPKDGGPGPGKAPWPGDFGTTAKE
    SSGNGAPEERLRENGDALSREGSLGPLPGSSAQPHKGILKKKCLPTISEK
    SSLLRLPLEQCTGSSRGSSASEGSRGGPPPRPPPRQSLQEQLNGVMPIAM
    SIKAGTVDEDSSGSEFLFFNFLH

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • CELSR2
  • Full Name
  • Cadherin EGF LAG seven-pass G-type receptor 2
  • Introduction
  • The protein encoded by this gene is a member of the flamingo subfamily, part of the cadherin superfamily. The flamingo subfamily consists of nonclassic-type cadherins; a subpopulation that does not interact with catenins. The flamingo cadherins are located at the plasma membrane and have nine cadherin domains, seven epidermal growth factor-like repeats and two laminin A G-type repeats in their ectodomain. They also have seven transmembrane domains, a characteristic unique to this subfamily. It is postulated that these proteins are receptors involved in contact-mediated communication, with cadherin domains acting as homophilic binding regions and the EGF-like domains involved in cell adhesion and receptor-ligand interactions. The specific function of this particular member has not been determined.
  • Alternative Names
  • EGFL2; MEGF3; ADGRC2; CDHF10; Flamingo1; cadherin EGF LAG seven-pass G-type receptor 2; EGF-like protein 2 EGF-like-domain, multiple 2; adhesion G protein-coupled receptor C2; cadherin family member 10; cadherin, EGF LAG seven-pass G-type receptor 2 (flamingo homolog, Drosophila); epidermal growth factor-like 2; epidermal growth factor-like protein 2; flamingo homolog 3; multiple EGF-like domains protein 3; multiple epidermal growth factor-like domains 3; multiple epidermal growth factor-like domains protein 3; CELSR2; Cadherin EGF LAG seven-pass G-type receptor 2

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