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Magic™ Membrane Protein Human CLTRN (Collectrin, amino acid transport regulator) Full Length (CAT#: MPC1503K) Made to Order

This product is a 25.2 kDa Human CLTRN membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • CLTRN
  • Protein Length
  • Full length
  • Protein Class
  • Transporter
  • Molecular Weight
  • 25.2 kDa
  • TMD
  • 1
  • Sequence
  • MLWLLFFLVTAIHAELCQPGAENAFKVRLSIRTALGDKAYAWDTNEEYLF
    KAMVAFSMRKVPNREATEISHVLLCNVTQRVSFWFVVTDPSKNHTLPAVE
    VQSAIRMNKNRINNAFFLNDQTLEFLKIPSTLAPPMDPSVPIWIIIFGVI
    FCIIIVAIALLILSGIWQRRRKNKEPSEVDDAEDKCENMITIENGIPSDP
    LDMKGGHINDAFMTEDERLTPL

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • CLTRN
  • Full Name
  • Collectrin, amino acid transport regulator
  • Introduction
  • This gene encodes a type 1 transmembrane protein that is important for trafficking amino acid transporters to the apical brush border of proximal tubules. The encoded protein binds to amino acid transporters and regulates their expression on the plasma membrane. It also plays a role in controlling insulin exocytosis by regulating formation of the SNARE (soluble N-ethylmaleimide-sensitive-factor attachment protein receptor) complex in pancreatic beta cells. The extracellular domain of the encoded protein may be cleaved and shed from the plasma membrane specifically in pancreatic beta cells.
  • Alternative Names
  • CLTRN; NX17; NX-17; TMEM27; collectrin; kidney-specific membrane protein; transmembrane protein 27; Collectrin, amino acid transport regulator

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