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Magic™ Membrane Protein Human GJB2 (Gap junction protein beta 2) Full Length (CAT#: MPC0534K) Made to Order

Datasheet
This product is a 26.2 kDa Human GJB2 membrane protein expressed in Baculovirus/Insect expression system. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • GJB2
  • Protein Length
  • Full length
  • Protein Class
  • Transporter
  • Molecular Weight
  • 26.2 kDa
  • TMD
  • 4
  • Sequence
  • MDWGTLQTILGGVNKHSTSIGKIWLTVLFIFRIMILVVAAKEVWGDEQAD
    FVCNTLQPGCKNVCYDHYFPISHIRLWALQLIFVSTPALLVAMHVAYRRH
    EKKRKFIKGEIKSEFKDIEEIKTQKVRIEGSLWWTYTSSIFFRVIFEAAF
    MYVFYVMYDGFSMQRLVKCNAWPCPNTVDCFVSRPTEKTVFTVFMIAVSG
    ICILLNVTELCYLLIRYCSGKSKKPV

Product Description

  • Expression Systems
  • Baculovirus/Insect expression system
  • Tag
  • 6xHis tag at the C-terminus
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • GJB2
  • Full Name
  • Gap junction protein beta 2
  • Introduction
  • This gene encodes a member of the gap junction protein family. The gap junctions were first characterized by electron microscopy as regionally specialized structures on plasma membranes of contacting adherent cells. These structures were shown to consist of cell-to-cell channels that facilitate the transfer of ions and small molecules between cells. The gap junction proteins, also known as connexins, purified from fractions of enriched gap junctions from different tissues differ. According to sequence similarities at the nucleotide and amino acid levels, the gap junction proteins are divided into two categories, alpha and beta. Mutations in this gene are responsible for as much as 50% of pre-lingual, recessive deafness.
  • Alternative Names
  • HID; KID; PPK; BAPS; CX26; DFNA3; DFNB1; NSRD1; DFNA3A; DFNB1A; gap junction beta-2 protein; connexin 26; gap junction beta 2 proteinc; gap junction protein, beta 2, 26kDa; mutant gap junction beta 2 protein; mutant gap junction protein beta 2; GJB2; Gap junction protein beta 2

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