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Magic™ Membrane Protein Human KIRREL1 (Kirre like nephrin family adhesion molecule 1) Expressed in HEK293 for Antibody Discovery, Partial (17-493aa) (CAT#: MPX0777K)

Datasheet
This product is a 53 kDa Human KIRREL1 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • KIRREL1
  • Protein Length
  • Partial (17-493aa)
  • Protein Class
  • Receptor
  • Molecular Weight
  • 53 kDa
  • TMD
  • 1
  • Sequence
  • QGTQTRFSQEPADQTVVAGQRAVLPCVLLNYSGI
    VQWTKDGLALGMGQGLKAWPRYRVVGSADAGQYNLEITDAELSDDASYEC
    QATEAALRSRRAKLTVLIPPEDTRIDGGPVILLQAGTPHNLTCRAFNAKP
    AATIIWFRDGTQQEGAVASTELLKDGKRETTVSQLLINPTDLDIGRVFTC
    RSMNEAIPSGKETSIELDVHHPPTVTLSIEPQTVQEGERVVFTCQATANP
    EILGYRWAKGGFLIEDAHESRYETNVDYSFFTEPVSCEVHNKVGSTNVST
    LVNVHFAPRIVVDPKPTTTDIGSDVTLTCVWVGNPPLTLTWTKKDSNMVL
    SNSNQLLLKSVTQADAGTYTCRAIVPRIGVAEREVPLYVNGPPIISSEAV
    QYAVRGDGGKVECFIGSTPPPDRIAWAWKENFLEVGTLERYTVERTNSGS
    GVLSTLTINNVMEADFQTHYNCTAWNSFGPGTAIIQLEEREVL

Product Description

  • Activity
  • Yes
  • Expression Systems
  • HEK293
  • Tag
  • 6xHis tag at the C-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Reconstitute at 500 μg/mL in PBS.
  • Endotoxin
  • <0.10 EU per 1 μg of the protein by the LAL method.
  • Purity
  • >95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
  • Buffer
  • Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.

Target

  • Target Protein
  • KIRREL1
  • Full Name
  • Kirre like nephrin family adhesion molecule 1
  • Introduction
  • NEPH1 is a member of the nephrin-like protein family, which includes NEPH2 (MIM 607761) and NEPH3 (MIM 607762). The cytoplasmic domains of these proteins interact with the C terminus of podocin (NPHS2; MIM 604766), and the genes are expressed in kidney podocytes, cells involved in ensuring size- and charge-selective ultrafiltration.
  • Alternative Names
  • KIRREL1; NEPH1; KIRREL; NPHS23; kin of IRRE-like protein 1; kin of IRRE like; kin of irregular chiasm-like protein 1; nephrin related; nephrin-like protein 1; Kirre like nephrin family adhesion molecule 1

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