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Magic™ Membrane Protein Human KL (Klotho) Full Length (CAT#: MPC2021K) Made to Order

This product is a 116.1 kDa Human KL membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • KL
  • Protein Length
  • Full length
  • Protein Class
  • Receptor
  • Molecular Weight
  • 116.1 kDa
  • TMD
  • 1
  • Sequence
  • MPASAPPRRPRPPPPSLSLLLVLLGLGGRRLRAEPGDGAQTWARFSRPPA
    PEAAGLFQGTFPDGFLWAVGSAAYQTEGGWQQHGKGASIWDTFTHHPLAP
    PGDSRNASLPLGAPSPLQPATGDVASDSYNNVFRDTEALRELGVTHYRFS
    ISWARVLPNGSAGVPNREGLRYYRRLLERLRELGVQPVVTLYHWDLPQRL
    QDAYGGWANRALADHFRDYAELCFRHFGGQVKYWITIDNPYVVAWHGYAT
    GRLAPGIRGSPRLGYLVAHNLLLAHAKVWHLYNTSFRPTQGGQVSIALSS
    HWINPRRMTDHSIKECQKSLDFVLGWFAKPVFIDGDYPESMKNNLSSILP
    DFTESEKKFIKGTADFFALCFGPTLSFQLLDPHMKFRQLESPNLRQLLSW
    IDLEFNHPQIFIVENGWFVSGTTKRDDAKYMYYLKKFIMETLKAIKLDGV
    DVIGYTAWSLMDGFEWHRGYSIRRGLFYVDFLSQDKMLLPKSSALFYQKL
    IEKNGFPPLPENQPLEGTFPCDFAWGVVDNYIQVDTTLSQFTDLNVYLWD
    VHHSKRLIKVDGVVTKKRKSYCVDFAAIQPQIALLQEMHVTHFRFSLDWA
    LILPLGNQSQVNHTILQYYRCMASELVRVNITPVVALWQPMAPNQGLPRL
    LARQGAWENPYTALAFAEYARLCFQELGHHVKLWITMNEPYTRNMTYSAG
    HNLLKAHALAWHVYNEKFRHAQNGKISIALQADWIEPACPFSQKDKEVAE
    RVLEFDIGWLAEPIFGSGDYPWVMRDWLNQRNNFLLPYFTEDEKKLIQGT
    FDFLALSHYTTILVDSEKEDPIKYNDYLEVQEMTDITWLNSPSQVAVVPW
    GLRKVLNWLKFKYGDLPMYIISNGIDDGLHAEDDQLRVYYMQNYINEALK
    AHILDGINLCGYFAYSFNDRTAPRFGLYRYAADQFEPKASMKHYRKIIDS
    NGFPGPETLERFCPEEFTVCTECSFFHTRKSLLAFIAFLFFASIISLSLI
    FYYSKKGRRSYK

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • KL
  • Full Name
  • Klotho
  • Introduction
  • This gene encodes a type-I membrane protein that is related to beta-glucosidases. Reduced production of this protein has been observed in patients with chronic renal failure (CRF), and this may be one of the factors underlying the degenerative processes (e.g., arteriosclerosis, osteoporosis, and skin atrophy) seen in CRF. Also, mutations within this protein have been associated with ageing and bone loss.
  • Alternative Names
  • KL; HFTC3; Klotho

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