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Magic™ Membrane Protein Human NECTIN3 (Nectin cell adhesion molecule 3) Expressed in NS0 for Antibody Discovery, Partial (56-400aa) (CAT#: MPX0751K)

Datasheet
This product is a 38.7 kDa Human NECTIN3 membrane protein expressed in NS0. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • NECTIN3
  • Protein Length
  • Partial (56-400aa)
  • Protein Class
  • Cell adhesion
  • Molecular Weight
  • 38.7 kDa
  • TMD
  • 1
  • Sequence
  • LAGPI
    IVEPHVTAVWGKNVSLKCLIEVNETITQISWEKIHGKSSQTVAVHHPQYGFSVQGEYQGR
    VLFKNYSLNDATITLHNIGFSDSGKYICKAVTFPLGNAQSSTTVTVLVEPTVSLIKGPDS
    LIDGGNETVAAICIAATGKPVAHIDWEGDLGEMESTTTSFPNETATIISQYKLFPTRFAR
    GRRITCVVKHPALEKDIRYSFILDIQYAPEVSVTGYDGNWFVGRKGVNLKCNADANPPPF
    KSVWSRLDGQWPDGLLASDNTLHFVHPLTFNYSGVYICKVTNSLGQRSDQKVIYISDPPT
    TTTLQPTIQWHPSTADIEDLATEPKKLPFPLSTLATIKDD

Product Description

  • Activity
  • Yes
  • Expression Systems
  • NS0
  • Tag
  • 6xHis tag at the C-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Reconstitute at 100 μg/mL in sterile PBS.
  • Endotoxin
  • <0.10 EU per 1 μg of the protein by the LAL method.
  • Purity
  • >95%, by SDS-PAGE under reducing conditions and visualized by silver stain
  • Buffer
  • Lyophilized from a 0.2 μm filtered solution in PBS.

Target

  • Target Protein
  • NECTIN3
  • Full Name
  • Nectin cell adhesion molecule 3
  • Introduction
  • This gene encodes a member of the nectin family of proteins, which function as adhesion molecules at adherens junctions. This family member interacts with other nectin-like proteins and with afadin, a filamentous actin-binding protein involved in the regulation of directional motility, cell proliferation and survival. This gene plays a role in ocular development involving the ciliary body. Mutations in this gene are believed to result in congenital ocular defects. Alternative splicing results in multiple transcript variants.
  • Alternative Names
  • NECTIN3; PPR3; PRR3; CD113; PVRL3; PVRR3; CDW113; NECTIN-3; nectin-3; nectin 3; poliovirus receptor-related 3; poliovirus receptor-related protein 3; Nectin cell adhesion molecule 3

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