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Magic™ Membrane Protein Human RTN3 (Reticulon 3) Full Length (CAT#: MPC1861K) Made to Order

Datasheet
This product is a 112.6 kDa Human RTN3 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • RTN3
  • Protein Length
  • Full length
  • Protein Class
  • Transporter
  • Molecular Weight
  • 112.6 kDa
  • TMD
  • 3
  • Sequence
  • MAEPSAATQSHSISSSSFGAEPSAPGGGGSPGACPALGTKSCSSSCADSF
    VSSSSSQPVSLFSTSQEGLSSLCSDEPSSEIMTSSFLSSSEIHNTGLTIL
    HGEKSHVLGSQPILAKEGKDHLDLLDMKKMEKPQGTSNNVSDSSVSLAAG
    VHCDRPSIPASFPEHPAFLSKKIGQVEEQIDKETKNPNGVSSREAKTALD
    ADDRFTLLTAQKPPTEYSKVEGIYTYSLSPSKVSGDDVIEKDSPESPFEV
    IIDKAAFDKEFKDSYKESTDDFGSWSVHTDKESSEDISETNDKLFPLRNK
    EAGRYPMSALLSRQFSHTNAALEEVSRCVNDMHNFTNEILTWDLVPQVKQ
    QTDKSSDCITKTTGLDMSEYNSEIPVVNLKTSTHQKTPVCSIDGSTPITK
    STGDWAEASLQQENAITGKPVPDSLNSTKEFSIKGVQGNMQKQDDTLAEL
    PGSPPEKCDSLGSGVATVKVVLPDDHLKDEMDWQSSALGEITEADSSGES
    DDTVIEDITADTSFENNKIQAEKPVSIPSAVVKTGEREIKEIPSCEREEK
    TSKNFEELVSDSELHQDQPDILGRSPASEAACSKVPDTNVSLEDVSEVAP
    EKPITTENPKLPSTVSPNVFNETEFSLNVTTSAYLESLHGKNVKHIDDSS
    PEDLIAAFTETRDKGIVDSERNAFKAISEKMTDFKTTPPVEVLHENESGG
    SEIKDIGSKYSEQSKETNGSEPLGVFPTQGTPVASLDLEQEQLTIKALKE
    LGERQVEKSTSAQRDAELPSEEVLKQTFTFAPESWPQRSYDILERNVKNG
    SDLGISQKPITIRETTRVDAVSSLSKTELVKKHVLARLLTDFSVHDLIFW
    RDVKKTGFVFGTTLIMLLSLAAFSVISVVSYLILALLSVTISFRIYKSVI
    QAVQKSEEGHPFKAYLDVDITLSSEAFHNYMNAAMVHINRALKLIIRLFL
    VEDLVDSLKLAVFMWLMTYVGAVFNGITLLILAELLIFSVPIVYEKYKTQ
    IDHYVGIARDQTKSIVEKIQAKLPGIAKKKAE

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • RTN3
  • Full Name
  • Reticulon 3
  • Introduction
  • This gene belongs to the reticulon family of highly conserved genes that are preferentially expressed in neuroendocrine tissues. This family of proteins interact with, and modulate the activity of beta-amyloid converting enzyme 1 (BACE1), and the production of amyloid-beta. An increase in the expression of any reticulon protein substantially reduces the production of amyloid-beta, suggesting that reticulon proteins are negative modulators of BACE1 in cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene, and pseudogenes of this gene are located on chromosomes 4 and 12.
  • Alternative Names
  • RTN3; HAP; ASYIP; NSPL2; NSPLII; RTN3-A1; reticulon-3; ASY interacting protein; NSP-like protein 2; NSP-like protein II; homolog of ASY protein; neuroendocrine-specific protein-like 2; neuroendocrine-specific protein-like II; Reticulon 3

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