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Magic™ Membrane Protein Human SCARF1 (Scavenger receptor class F member 1) Expressed in NS0 for Antibody Discovery, Partial (20-421aa) (CAT#: MPX0438K)

Datasheet
This product is a 69.1 kDa Human SCARF1 membrane protein expressed in NS0. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • SCARF1
  • Protein Length
  • Partial (20-421aa)
  • Protein Class
  • Cell adhesion
  • Molecular Weight
  • 69.1 kDa
  • TMD
  • 1
  • Sequence
  • SELDPKGQHVCVASSPSAELQCCAGWRQKDQ
    ECTIPICEGPDACQKDEVCVKPGLCRCKPGFFGAHCSSRCPGQYWGPDCR
    ESCPCHPHGQCEPATGACQCQADRWGARCEFPCACGPHGRCDPATGVCHC
    EPGWWSSTCRRPCQCNTAAARCEQATGACVCKPGWWGRRCSFRCNCHGSP
    CEQDSGRCACRPGWWGPECQQQCECVRGRCSAASGECTCPPGFRGARCEL
    PCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEPGWNGTQCQQPCLPG
    TFGESCEQQCPHCRHGEACEPDTGHCQRCDPGWLGPRCEDPCPTGTFGED
    CGSTCPTCVQGSCDTVTGDCVCSAGYWGPSCNASCPAGFHGNNCSVPCEC
    PEGLCHPVSGSCQPGSGSRDT

Product Description

  • Activity
  • Yes
  • Expression Systems
  • NS0
  • Tag
  • hIgG1 Fc tag at the C-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Reconstitute at 100 μg/mL in sterile PBS.
  • Endotoxin
  • <0.10 EU per 1 μg of the protein by the LAL method.
  • Purity
  • >90%, by SDS-PAGE under reducing conditions and visualized by silver stain
  • Buffer
  • Lyophilized from a 0.2 μm filtered solution in PBS.

Target

  • Target Protein
  • SCARF1
  • Full Name
  • Scavenger receptor class F member 1
  • Introduction
  • The protein encoded by this gene is a scavenger receptor that is expressed in endothelial cells. It regulates the uptake of chemically modified low density lipoproteins, including acetylated low density lipoprotein (Ac-LDL), and it may be involved in atherogenesis. This gene is regulated by the transcription factors ZNF444/EZF-2 and SP1. Alternative splicing results in multiple transcript variants.
  • Alternative Names
  • SCARF1; SREC; SREC1; SREC-I; scavenger receptor class F member 1; acetyl LDL receptor; scavenger receptor expressed by endothelial cells 1; Scavenger receptor class F member 1

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