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Magic™ Membrane Protein Human SGCE (Sarcoglycan epsilon) Full Length (CAT#: MPC1228K) Made to Order

Datasheet
This product is a 49.8 kDa Human SGCE membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • SGCE
  • Protein Length
  • Full length
  • Protein Class
  • Cell adhesion
  • Molecular Weight
  • 49.8 kDa
  • TMD
  • 1
  • Sequence
  • MQLPRWWELGDPCAWTGQGRGTRRMSPATTGTFLLTVYSIFSKVHSDRNV
    YPSAGVLFVHVLEREYFKGEFPPYPKPGEISNDPITFNTNLMGYPDRPGW
    LRYIQRTPYSDGVLYGSPTAENVGKPTIIEITAYNRRTFETARHNLIINI
    MSAEDFPLPYQAEFFIKNMNVEEMLASEVLGDFLGAVKNVWQPERLNAIN
    ITSALDRGGRVPLPINDLKEGVYVMVGADVPFSSCLREVENPQNQLRCSQ
    EMEPVITCDKKFRTQFYIDWCKISLVDKTKQVSTYQEVIRGEGILPDGGE
    YKPPSDSLKSRDYYTDFLITLAVPSAVALVLFLILAYIMCCRREGVEKRN
    MQTPDIQLVHHSAIQKSTKELRDMSKNREIAWPLSTLPVFHPVTGEIIPP
    LHTDNYDSTNMPLMQTQQNLPHQTQIPQQQTTGKWYP

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • SGCE
  • Full Name
  • Sarcoglycan epsilon
  • Introduction
  • This gene encodes the epsilon member of the sarcoglycan family. Sarcoglycans are transmembrane proteins that are components of the dystrophin-glycoprotein complex, which link the actin cytoskeleton to the extracellular matrix. Unlike other family members which are predominantly expressed in striated muscle, the epsilon sarcoglycan is more broadly expressed. Mutations in this gene are associated with myoclonus-dystonia syndrome. This gene is imprinted, with preferential expression from the paternal allele. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. A pseudogene associated with this gene is located on chromosome 2.
  • Alternative Names
  • SGCE; ESG; DYT11; epsilon-SG; epsilon-sarcoglycan; dystonia 11, myoclonic; Sarcoglycan epsilon

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