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Magic™ Membrane Protein Human SLCO1B3 (Solute carrier organic anion transporter family member 1B3) Full Length (CAT#: MPC0931K) Made to Order

This product is a 77.4 kDa Human SLCO1B3 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • SLCO1B3
  • Protein Length
  • Full length
  • Protein Class
  • Transporter
  • Molecular Weight
  • 77.4 kDa
  • TMD
  • 12
  • Sequence
  • MDQHQHLNKTAESASSEKKKTRRCNGFKMFLAALSFSYIAKALGGIIMKI
    SITQIERRFDISSSLAGLIDGSFEIGNLLVIVFVSYFGSKLHRPKLIGIG
    CLLMGTGSILTSLPHFFMGYYRYSKETHINPSENSTSSLSTCLINQTLSF
    NGTSPEIVEKDCVKESGSHMWIYVFMGNMLRGIGETPIVPLGISYIDDFA
    KEGHSSLYLGSLNAIGMIGPVIGFALGSLFAKMYVDIGYVDLSTIRITPK
    DSRWVGAWWLGFLVSGLFSIISSIPFFFLPKNPNKPQKERKISLSLHVLK
    TNDDRNQTANLTNQGKNVTKNVTGFFQSLKSILTNPLYVIFLLLTLLQVS
    SFIGSFTYVFKYMEQQYGQSASHANFLLGIITIPTVATGMFLGGFIIKKF
    KLSLVGIAKFSFLTSMISFLFQLLYFPLICESKSVAGLTLTYDGNNSVAS
    HVDVPLSYCNSECNCDESQWEPVCGNNGITYLSPCLAGCKSSSGIKKHTV
    FYNCSCVEVTGLQNRNYSAHLGECPRDNTCTRKFFIYVAIQVINSLFSAT
    GGTTFILLTVKIVQPELKALAMGFQSMVIRTLGGILAPIYFGALIDKTCM
    KWSTNSCGAQGACRIYNSVFFGRVYLGLSIALRFPALVLYIVFIFAMKKK
    FQGKDTKASDNERKVMDEANLEFLNNGEHFVPSAGTDSKTCNLDMQDNAA
    AN

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • SLCO1B3
  • Full Name
  • Solute carrier organic anion transporter family member 1B3
  • Introduction
  • This gene encodes a liver-specific member of the organic anion transporter family. The encoded protein is a transmembrane receptor that mediates the sodium-independent uptake of endogenous and xenobiotic compounds and plays a critical role in bile acid and bilirubin transport. Mutations in this gene are a cause of Rotor type hyperbilirubinemia. Alternative splicing of this gene and the use of alternative promoters results in transcript variants encoding different isoforms that differ in their tissue specificity.
  • Alternative Names
  • LST3; HBLRR; LST-2; OATP8; OATP-8; OATP1B3; SLC21A8; LST-3TM13; solute carrier organic anion transporter family member 1B3; liver-specific organic anion transporter 2; liver-specific organic anion transporter 3TM13; organic anion transporter 8; organic anion transporter LST-3c; organic anion-transporting polypeptide 8; solute carrier family 21 (organic anion transporter), member 8; SLCO1B3; Solute carrier organic anion transporter family member 1B3

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