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Magic™ Membrane Protein Human SPG7 (SPG7 matrix AAA peptidase subunit, paraplegin) Full Length (CAT#: MPC3494K) Made to Order

Datasheet
This product is a made-to-order Human SPG7 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • SPG7
  • Protein Length
  • Full length
  • Protein Class
  • Protease
  • TMD
  • 2
  • Sequence
  • MAVLLLLLRALRRGPGPGPRPLWGPGPAWSPGFPARPGRGRPYMASRPPG
    DLAEAGGRALQSLQLRLLTPTFEGINGLLLKQHLVQNPVRLWQLLGGTFY
    FNTSRLKQKNKEKDKSKGKAPEEDEEERRRRERDDQMYRERLRTLLVIAV
    VMSLLNALSTSGGSISWNDFVHEMLAKGEVQRVQVVPESDVVEVYLHPGA
    VVFGRPRLALMYRMQVANIDKFEEKLRAAEDELNIEAKDRIPVSYKRTGF
    FGNALYSVGMTAVGLAILWYVFRLAGMTGREGGFSAFNQLKMARFTIVDG
    KMGKGVSFKDVAGMHEAKLEVREFVDYLKSPERFLQLGAKVPKGALLLGP
    PGCGKTLLAKAVATEAQVPFLAMAGPEFVEVIGGLGAARVRSLFKEARAR
    APCIVYIDEIDAVGKKRSTTMSGFSNTEEEQTLNQLLVEMDGMGTTDHVI
    VLASTNRADILDGALMRPGRLDRHVFIDLPTLQERREIFEQHLKSLKLTQ
    SSTFYSQRLAELTPGFSGADIANICNEAALHAAREGHTSVHTLNFEYAVE
    RVLAGTAKKSKILSKEEQKVVAFHESGHALVGWMLEHTEAVMKVSITPRT
    NAALGFAQMLPRDQHLFTKEQLFERMCMALGGRASEALSFNEVTSGAQDD
    LRKVTRIAYSMVKQFGMAPGIGPISFPEAQEGLMGIGRRPFSQGLQQMMD
    HEARLLVAKAYRHTEKVLQDNLDKLQALANALLEKEVINYEDIEALIGPP
    PHGPKKMIAPQRWIDAQREKQDLGEEETEETQQPPLGGEEPTWPK

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements (Detergent, Liposome, Nanodisc, SMALPs, VLP)

Target

  • Target Protein
  • SPG7
  • Full Name
  • SPG7 matrix AAA peptidase subunit, paraplegin
  • Introduction
  • This gene encodes a mitochondrial metalloprotease protein that is a member of the AAA family. Members of this protein family share an ATPase domain and have roles in diverse cellular processes including membrane trafficking, intracellular motility, organelle biogenesis, protein folding, and proteolysis. Mutations in this gene cause autosomal recessive spastic paraplegia 7. Two transcript variants encoding distinct isoforms have been identified.
  • Alternative Names
  • SPG7; CAR; PGN; CMAR; SPG5C; paraplegin; SPG7, paraplegin matrix AAA peptidase subunit; cell matrix adhesion regulator; spastic paraplegia 7 (pure and complicated autosomal recessive); spastic paraplegia 7 protein; SPG7 matrix AAA peptidase subunit, paraplegin

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