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Magic™ Membrane Protein Human SPINT2 (Serine peptidase inhibitor, Kunitz type 2) (CAT#: MP0255J)

This product is a 25.4 kDa Human SPINT2 membrane protein expressed in HEK293T. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • SPINT2
  • Protein Length
  • Full-length
  • Protein Class
  • Transmembrane
  • Molecular Weight
  • 25.4 kDa
  • TMD
  • 1
  • Sequence
  • MAQLCGLRRSRAFLALLGSLLLSGVLAADRERSIHDFCLVSKVVGRCRASMPRWWYNVTDGSCQLFVYGG
    CDGNSNNYLTKEECLKKCATVTENATGDLATSRNAADSSVPSAPRRQDSEDHSSDMFNYEEYCTANAVTG
    PCRASFPRWYFDVERNSCNNFIYGGCRGNKNSYRSEEACMLRCFRQQENPPLPLGSKVVLLAGLFVMVLI
    LFLGASMVYLIRVARRNQERALRTVWSSGDDKEQLVKNTYVL

Product Description

  • Expression Systems
  • HEK293T
  • Tag
  • C-Myc/DDK
  • Purification
  • Anti-DDK affinity column followed by conventional chromatography steps
  • Purity
  • > 80% as determined by SDS-PAGE and Coomassie blue staining
  • Buffer
  • 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Target

  • Target Protein
  • SPINT2
  • Full Name
  • Serine peptidase inhibitor, Kunitz type 2
  • Introduction
  • This gene encodes a transmembrane protein with two extracellular Kunitz domains that inhibits a variety of serine proteases. The protein inhibits HGF activator which prevents the formation of active hepatocyte growth factor. This gene is a putative tumor suppressor, and mutations in this gene result in congenital sodium diarrhea. Multiple transcript variants encoding different isoforms have been found for this gene.
  • Alternative Names
  • PB; Kop; HAI2; DIAR3; HAI-2; hepatocyte growth factor activator inhibitor type 2; serine protease inhibitor, Kunitz type, 2; testicular tissue protein Li 183

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