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Magic™ Membrane Protein Human TBXAS1 (Thromboxane A synthase 1) Full Length (CAT#: MPC3481K) Made to Order

This product is a made-to-order Human TBXAS1 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • TBXAS1
  • Protein Length
  • Full length
  • Protein Class
  • Oxidoreductase
  • TMD
  • 4
  • Sequence
  • MEALGFLKLEVNGPMVTVALSVALLALLKWYSTSAFSRLEKLGLRHPKPS
    PFIGNLTFFRQGFWESQMELRKLYGPLCGYYLGRRMFIVISEPDMIKQVL
    VENFSNFTNRMASGLEFKSVADSVLFLRDKRWEEVRGALMSAFSPEKLNE
    MVPLISQACDLLLAHLKRYAESGDAFDIQRCYCNYTTDVVASVAFGTPVD
    SWQAPEDPFVKHCKRFFEFCIPRPILVLLLSFPSIMVPLARILPNKNRDE
    LNGFFNKLIRNVIALRDQQAAEERRRDFLQMVLDARHSASPMGVQDFDIV
    RDVFSSTGCKPNPSRQHQPSPMARPLTVDEIVGQAFIFLIAGYEIITNTL
    SFATYLLATNPDCQEKLLREVDVFKEKHMAPEFCSLEEGLPYLDMVIAET
    LRMYPPAFRFTREAAQDCEVLGQRIPAGAVLEMAVGALHHDPEHWPSPET
    FNPERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKF
    RFQACPETQVPLQLESKSALGPKNGVYIKIVSR

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements (Detergent, Liposome, Nanodisc, SMALPs, VLP)

Target

  • Target Protein
  • TBXAS1
  • Full Name
  • Thromboxane A synthase 1
  • Introduction
  • This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. However, this protein is considered a member of the cytochrome P450 superfamily on the basis of sequence similarity rather than functional similarity. This endoplasmic reticulum membrane protein catalyzes the conversion of prostglandin H2 to thromboxane A2, a potent vasoconstrictor and inducer of platelet aggregation. The enzyme plays a role in several pathophysiological processes including hemostasis, cardiovascular disease, and stroke. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
  • Alternative Names
  • TBXAS1; TS; TXS; CYP5; THAS; TXAS; CYP5A1; GHOSAL; BDPLT14; thromboxane-A synthase; TXA synthase; cytochrome P450 5A1; cytochrome P450, family 5, subfamily A, polypeptide 1; hydroperoxy icosatetraenoate dehydratase; platelet, cytochrome P450, subfamily V; thromboxane A synthase 1 (platelet); Thromboxane A synthase 1

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