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Magic™ Membrane Protein Human TMEM107 (Transmembrane protein 107) Full Length (CAT#: MPC1314K) Made to Order

This product is a 15.5 kDa Human TMEM107 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • TMEM107
  • Protein Length
  • Full length
  • Protein Class
  • Transporter
  • Molecular Weight
  • 15.5 kDa
  • TMD
  • 4
  • Sequence
  • MGRVSGLVPSRFLTLLAHLVVVITLFWSRDSNIQACLPLTFTPEEYDKQD
    IQLVAALSVTLGLFAVELAGFLSGVSMFNSTQSLISIGAHCSASVALSFF
    IFERWECTTYWYIFVFCSALPAVTEMALFVTVFGLKKKPF

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • TMEM107
  • Full Name
  • Transmembrane protein 107
  • Introduction
  • This gene encodes a transmembrane protein and component of the primary cilia transition zone. The encoded protein regulates ciliogenesis and ciliary protein composition. Human fibroblasts expressing a mutant allele of this gene exhibit reduced numbers of cilia, altered cilia length, and impaired sonic hedgehog signaling. In human patients, different mutations in this gene cause different ciliopathies, including Meckel-Gruber syndrome and orofaciodigital syndrome.
  • Alternative Names
  • TMEM107; MKS13; JBTS29; GRVS638; PRO1268; UNQ638/PRO1268; DC20; Transmembrane protein 107

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