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Magic™ Membrane Protein Mouse CLEC7A Expressed in NS0, Partial (69-244aa) (CAT#: S01YF-0223-KX2)

Datasheet
This product is a Mouse CLEC7A membrane protein expressed in NS0. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Mouse
  • Target Protein
  • CLEC7A
  • Protein Length
  • Partial (69-244aa)
  • Protein Class
  • Receptor; Immunity
  • Molecular Weight
  • 21.6 kDa
  • TMD
  • 1
  • Sequence
  • Phe69-Leu244 (Accession # Q6QLQ4)

Product Description

  • Activity
  • Yes
  • Expression Systems
  • NS0
  • Tag
  • 10xHis tag at the N-terminus
  • Protein Format
  • Soluble
  • Endotoxin
  • <0.01 EU per 1 μg of the protein by the LAL method.
  • Purity
  • >95%, by SDS-PAGE under reducing conditions and visualized by silver stain
  • Buffer
  • Lyophilized from a 0.2 μm filtered solution in PBS.

Target

  • Target Protein
  • CLEC7A
  • Full Name
  • C-type lectin domain family 7, member a
  • Introduction
  • Predicted to enable (1->3)-beta-D-glucan binding activity and pattern recognition receptor activity. Predicted to be involved in several processes, including phagocytosis, recognition; positive regulation of cytokine production involved in inflammatory response; and response to fungus. Predicted to be active in cell surface. Is expressed in brain; gut; limb; musculature; and ventral grey horn. Human ortholog(s) of this gene implicated in aspergillosis and chronic mucocutaneous candidiasis. Orthologous to human CLEC7A (C-type lectin domain containing 7A).
  • Alternative Names
  • BGR; beta-GR; Clecsf12; C-type lectin domain family 7 member A; C-type (calcium dependent, carbohydrate recognition domain) lectin, superfamily member 12; C-type lectin superfamily member 12; DC-associated C-type lectin 1; beta-glucan receptor; dectin-1; dendritic cell-associated C-type lectin 1

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