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NativeExtract™ Human CYSLTR1 Membrane Protein (Full length, Super Nanodisc) (CAT#: S01YF-1023-KX289)

Datasheet
This product is recombinant Human CYSLTR1 protein in native nanodisc form. The synthetic compound we developed can solubilize the CYSLTR1 protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • CYSLTR1
  • Protein Length
  • Full length
  • Molecular Weight
  • 38.5kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • Flag tag at the C-terminus
  • Protein Format
  • Native Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • CYSLTR1
  • Full Name
  • Cysteinyl leukotriene receptor 1
  • Introduction
  • This gene encodes a member of the G-protein coupled receptor 1 family. The encoded protein is a receptor for cysteinyl leukotrienes, and is involved in mediating bronchoconstriction via activation of a phosphatidylinositol-calcium second messenger system. Activation of the encoded receptor results in contraction and proliferation of bronchial smooth muscle cells, eosinophil migration, and damage to the mucus layer in the lung. Upregulation of this gene is associated with asthma and dysregulation may also be implicated in cancer. Alternative splicing results in multiple transcript variants.
  • Alternative Names
  • CYSLT1; CYSLTR; CYSLT1R; HMTMF81; G-protein coupled receptor HG55; LTD4 receptor; cysteinyl leukotriene D4 receptor; CYSLTR1; Cysteinyl leukotriene receptor 1

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