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NativeExtract™ Human KCNK9 Membrane Protein (Full length, Super Nanodisc) (CAT#: S01YF-1023-KX424)

Datasheet
This product is recombinant Human KCNK9 protein in native nanodisc form. The synthetic compound we developed can solubilize the KCNK9 protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • KCNK9
  • Protein Length
  • Full length
  • Molecular Weight
  • 42.3 kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • Flag tag at the C-terminus
  • Protein Format
  • Native Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • KCNK9
  • Full Name
  • Potassium two pore domain channel subfamily K member 9
  • Introduction
  • This gene encodes a protein that contains multiple transmembrane regions and two pore-forming P domains and functions as a pH-dependent potassium channel. Amplification and overexpression of this gene have been observed in several types of human carcinomas. This gene is imprinted in the brain, with preferential expression from the maternal allele. A mutation in this gene was associated with Birk-Barel dysmorphism syndrome. Alternative splicing results in multiple transcript variants.
  • Alternative Names
  • KT3.2; TASK3; BIBARS; K2p9.1; TASK-3; TASK32; potassium channel subfamily K member 9; TWIK-related acid-sensitive K(+) channel 3; TWIK-related acid-sensitive K+ 3; acid-sensitive; potassium channel protein TASK-3; potassium 2-pore domain leak channel TASK3; potassium channel, two pore domain subfamily K, member 9; two pore K(+) channel KT3.2; two pore potassium channel KT3.2; KCNK9; Potassium two pore domain channel subfamily K member 9

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