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Porcine parvovirus Virus-like Particles (PPV VLPs) (CAT#: VLP-033YF)

Datasheet
Recombinant Porcine parvovirus Virus-like Particles (PPV VLPs) are produced in insect cells. VLP is mimicking the native 3D structure of viruses which can elicit strong immune responses. However, VLPs lack viral genomic material which makes them non-infectious, unable to replicate and enhance the safety during manufacture and administration. PPV VLPs can be used in the development of PPV diagnostics and in vaccine development and R&D (including use as an immunogen).

Product Specifications

  • Expression Systems
  • Baculovirus/Insect cell expression system
  • Form
  • Liquid
  • Alternative Names
  • Porcine parvovirus virus-like particles; PPV VLPs; Porcine parvovirus virus; PPV virus-like particles; VLPs; Virus-like Particles
  • Storage
  • Store at 4°C short term (2-4 weeks). Store at -80 °C long term. Avoid repeated freeze/thaw cycles.

Virus Background

  • Virus Family
  • Parvoviridae
  • Virus Species
  • Porcine parvovirus
  • Virus Overview
  • Porcine parvovirus causes reproductive failure of swine characterized by embryonic and fetal infection and death, usually in the absence of outward maternal clinical signs. The disease develops mainly when seronegative dams are exposed oronasally to the virus anytime during about the first half of gestation, and conceptuses are subsequently infected transplacentally before they become immunocompetent. There is no definitive evidence that infection of swine other than during gestation is of any clinical or economic significance. The virus is ubiquitous among swine throughout the world and is enzootic in most herds that have been tested. Diagnostic surveys have indicated that PPV is the major infectious cause of embryonic and fetal death. In addition to its direct causal role in reproductive failure, PPV can potentiate the effects of porcine circovirus type II (PCV2) infection in the clinical course of postweaning multisystemic wasting syndrome (PMWS).
  • Virus Structure
  • Non-enveloped, single-stranded DNA virus
  • Related Disease
  • Porcine parvovirus infection

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