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Bioinformatics Analysis Service

Background Services Advantages Q&As Resource

With years of research and development experience in the field of next-generation sequencing (NGS), Creative Biolabs has accumulated extensive experience in bioinformatics analysis to support whole genome sequencing (WGS), whole exome sequencing (WES), targeted sequencing, whole transcriptome sequencing (WTS) and immune repertoire sequencing. We can offer high-quality custom bioinformatics analysis services to meet every unique requirement of our clients.

Bioinformatics Analysis is Urgently Needed

The emergence of NGS platforms imposes increasing demands on statistical methods and bioinformatic tools for the analysis and the management of the huge amounts of data. NGS technologies have progressive advantages in terms of cost-effectiveness, unprecedented sequencing speed, high resolution and accuracy in genomic analyses, thus are playing an increasingly important role in fields of oncology and immunology. The combined power of NGS and bioinformatics analysis is vital for diagnostics and medical treatment.

Bioinformatics Analysis Service at Creative Biolabs

With years of research and development experience in the field of NGS, Creative Biolabs has established a cutting-edge SuPrecision™ platform to offer high-throughput sequencing services and high-quality bioinformatics analysis services.

Whole Genome Sequencing (WGS) Bioinformatics Analysis

Scientists from Creative Biolabs have developed a powerful pipeline for cancer WGS bioinformatic analysis with high accuracy. Our in-house pipeline has the capacity to process genomic data from large-scale subjects. Our strategy focuses on identifying genetic variations from WGS data. The genetic variants analysis pipeline consists of 1) quality control of raw data, 2) production of the clean data, 3) unspliced mapping of the clean data onto a reference genome, 4) post-alignment processing, 5) quality control of the mapped reads, 6) variant calling, annotation and prioritization.

Whole Exome Sequencing (WES) Bioinformatic Analysis

WES offers researchers the ability to use sequencing and analysis resources more efficiently by focusing on the most relevant portion of the genome. WES is especially suitable for patients who are looking for a unifying diagnosis of multiple medical problems. Creative Biolabs has accumulated extensive experience in WES service. Our scientists have developed a powerful in-house toolkit for cancer WES bioinformatic analysis with highly accurate interpretation. Copy number variations (CNVs) can be detected sensitively and challenging genes can be covered as much as possible.

Targeted Sequencing Bioinformatics Analysis

Creative Biolabs has explored a highly efficient tool that takes the information of the mapped reads and the coordinates of the targeted regions as input files and generates a comprehensive report. Customers can provide raw data from their NGS runs. Our bioinformatics solutions help researchers make sense of all the base calls. We can provide the most comprehensive information, including but not limited to 1) discovery of germline or somatic mutations, 2) detection and quantification rare variants, 3) detection of low-frequency alleles, 4) identification of biomarkers associated with a disease state.

Whole Transcriptome Sequencing (WTS) Bioinformatics Analysis

Scientists of Creative Biolabs have developed a range of different tools for WTS bioinformatics analysis pipeline. We can offer a series of solutions, from differential expression analysis to the identification of mutations and fusion transcripts. Our WTS bioinformatics analysis includes but is not limited to 1) biomarker discovery, 2) evolutionary study, 3) resistance study, 5) therapeutic development.

Immune Repertoire Bioinformatics Analysis

Creative Biolabs can offer repertoire sequencing service in diverse species, including human, mouse, rhesus monkey, alpaca, canine, rabbit, swine, feline, zebrafish, etc. Creative Biolabs has developed an efficient pipeline for repertoire sequencing analysis, starting from pre-processing, assignment, and analysis of repertoire properties. This pipeline is practical to solve bioinformatics problems in repertoires analysis.

Key Advantages of Our Bioinformatics Analysis Service Include but Are Not Limited to:

Highly accurate interpretation
Rapid and comprehensive discovery
Accurate results associated with the deep coverage
Flexibility to meet every unique client’s need
Highly seasoned bioinformatics specialists
Easy to understand for non-professionals
Secured and long-term secure cloud storage
Time-saving and price favorable

Equipped with world-leading technology platforms and professional scientific staff, Creative Biolabs has accomplished many high-throughput projects and corresponding bioinformatics analysis and we have provided our customers a great deal of useful data in the clinical diagnosis of many diseases, especially cancers. We offer turn-key or ala carte services customized to our client’s needs. Please contact us for more information and a detailed quote.

Q&As

Q: What types of NGS data can be analyzed using bioinformatics services?

A: Our bioinformatics services can analyze various types of NGS data, including whole genome sequencing, whole exome sequencing, RNA sequencing, and targeted sequencing. These services cover a wide range of applications, such as genomics, transcriptomics, epigenomics, and metagenomics.

Q: How does the bioinformatics analysis process work?

A: The process typically begins with a consultation to understand the project's specific requirements. This is followed by data submission, quality control, sequence alignment, variant calling, and functional annotation. Finally, results are reviewed with the client to ensure they meet the project's objectives.

Q: What role does data quality control play in bioinformatics analysis?

A: Data quality control is crucial for ensuring the accuracy and reliability of NGS results. It involves checking the sequencing data for errors, filtering out low-quality reads, and validating the accuracy of the sequence alignments and variant calls.

Q: What are the deliverables provided by bioinformatics analysis services?

A: Deliverables typically include raw sequencing data, processed data files, detailed analysis reports, visualizations such as graphs and charts, and interpretations of the findings. These comprehensive deliverables help researchers understand and communicate their results effectively.

Q: How do bioinformatics services customize analysis for specific research needs?

A: Bioinformatics services customize analysis by tailoring the data processing pipeline to the specific requirements of the research project. This includes selecting appropriate tools, setting parameters, and focusing on relevant biological questions, ensuring that the analysis meets the unique needs of each study.