NGS Service for Cancer 3D Model

NGS is a high-throughput sequencing technology that enables to sequence hundreds of thousands to millions of nucleic acid molecules at once in parallel. Supported by this powerful technology, the genetic profile of patient-derived tumor 3D models can be analyzed at the whole genome, whole exome, whole transcriptome, and several specific genes and amplicons, which provide opportunities for all-sided tumor profiling and discovery of personalized anti-tumor drugs. Creative Biolabs is a world-leading service provider that provides high-quality and cost-effective analysis services of patient-derived tumor 3D model based on NGS technology to promote your cancer research.

NGS Applications in Cancer Research

NGS, also known as high-throughput sequencing, allows rapid sequencing of the base pairs in DNA or RNA samples. It has a wide variety of applications including whole-genome sequencing, target sequencing, gene expression profiling, chromatin immunoprecipitation sequencing, small RNA sequencing, epigenomic sequencing, and so on. It is well known that cancer is the result of a series of gene mutations. Each cancer patient has a unique genetic fingerprint that determines the progression of the disease and the response to a certain therapy. Leveraging powerful NGS technology, we can sequence and analyze the entire genomes and transcriptome of cancer patients, discover all genetic variants associated with tumorigenesis including known and unknown. This provides a theoretical basis for the diagnosis, prognosis, and precise treatment of tumors.

The workflow of integrating omics data in cancer research and clinical application. Fig. 1 The workflow of integrating omics data in cancer research and clinical application. (Shyr, 2013)

Our capabilities

Based on NGS technology, we can analyze the genetic profile of patient-derived cancer 3D models at the levels of the whole genome, exome, and transcriptome, as well as specific gene areas of interest. Our capabilities include but are not limited to:

  • Whole Genome Sequencing (WGS): It allows detecting and analyzing the entire DNA make-up of cancer tissue in a single run and rapidly and deeply capturing a large number of cancer-related variations including single-nucleotide variants, small insertion/deletions, and copy number variants.
  • Targeted Sequencing: It allows deep sequencing of target gene regions.
  • Whole Transcriptome Sequencing: It is used to investigate all RNAs such as mRNA, miRNA, and LncRNA, allowing the detection of novel and rare transcripts and transcript variants.
  • Epigenome Sequencing: It enables us to analyze epigenetic factors such as genome-wide DNA methylation and DNA-protein interactions.

Features

  • Rich expertise in genetic detection and analysis
  • Proprietary robust sequencing platform for your choice
  • Rapidly and accurately capture all known or novel disease-causing genetic variations.
  • Providing reliable interpretation of genetic test results and personalized advice on cancer prevention and treatment.

Creative Biolabs is committing to provide the best gene sequencing and analysis services for cancer 3D model, helping you to uncover novel sight for the pathogenesis of tumors and novel anti-tumor drug targets. Please don't hesitate to contact us for more details.

Reference

  1. Shyr, Derek, and Qi Liu. "Next generation sequencing in cancer research and clinical application." Biological procedures online15 (2013): 1-11. Distributed under open access license CC BY 2.0, without modification.

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Note: Our sequencing services are for Research Use Only. Not For Clinical Diagnosis.
Related Services:
  1. Cancer 3D Model Development
  2. Therapeutic Validation in Cancer 3D Model
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