Therapeutic Validation in Cancer 3D Model
Therapeutic validation of the anti-tumor drug is an essential step in the process of preclinical drug development, aiming to evaluate the efficacy and toxicity of the drug to promote access to the clinical trial phase. Creative Biolabs has accumulated a lot of experience in drug development. We provide a wide range of flexible and reliable solutions for therapeutic validation of drug candidates in cancer 3D model, accelerating the process of drug development.
Drug Response Validation in Cancer 3D Model
Cancer 3D models, especially patient-derived cancer 3D models, closely recapitulate the genetic and morphological heterogeneous composition of the cancer cells in the original tumor. It has been revealed that 3D models are more predictive and informative compared with traditional 2D cell cultures. Hence, 3D models provide a more meaningful platform to study drug response. By incorporating 3D organoid models, candidate compounds can be screened more efficiently in vitro testing. The toxic or ineffective drug compounds can be eliminated in pre-clinical testing and the effective drug compounds enter into the stage of phase I–III clinical trials, the primary cost driver of pharmaceutical development. Therefore, using 3D organoid models to evaluate drug response increases the chances of successful development and reduces development costs.
Our capabilities
Our excellent scientists have rich professional knowledge and experience in cancer 3D model establishment and evaluation of drug response in the cancer models. We provide a wide range of solutions to study drug response in cancer 3D model, involved in the construction of cancer 3D model, designing comprehensive evaluation schemes for drug response, carrying out the schemes in cancer 3D model to screen more effective drugs.
We provide a variety of high-performance cancer 3D models, including organoids and spheroids derived from tumor cell lines and patient tumor tissues. The 3D models utilize the genetic and morphological heterogeneous composition of the cancer cells in the original tumor.
- Schematic Design
Our outstanding technical team provides a broad range of solutions for drug response evaluation in cancer 3D models. We can tailor the best project scheme to test the efficacy and toxicity of candidate drugs to accelerate the process of clinical application of a new drug. We also provide an optimal drug screening and evaluation strategy in patient-derived cancer 3D models to promote the development of personalized medicine.
- Project Implementation
A powerful technology platform and experienced technicists ensure the smooth progress of the project. Our platform is available for cell proliferation monitoring, antiangiogenesis assay, cell migration testing, and so on.
Features
- High-quality and low-cost services
- Skillful scientific team
- Advanced technology
- Best after-sale service
Creative Biolabs provides comprehensive, end-to-end drug response evaluation services in cancer 3D models to accelerate drug development. If you are interested in our services, please don’t hesitate to contact us for more details.