All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.
Recombinant Moloney murine leukemia virus (MMLV) retroviral vectors serve as efficient viral vector tools for introducing genes permanently into a wide variety of dividing cells, and provide an alternative to modify primary T cells. Creative biolabs has developed retroviral CAR vector pMMLV CD117 (AMG 191) h(BBζ), which is constructed for the engineering of T cells to target human CD117. The T cells are genetically modified through transduction with a retroviral vector expressing scFv of anti-CD117 antibody linked to CD137 (4-1BB) and CD3-zeta signaling domains. And the vector product was designed for the treatment of Gastrointestinal stromal tumors, Mast cell disease, Acute myelogenous lukemia, Piebaldism.
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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