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Anti-CD38 DNA-encoded mAb (DMAb), pVAX1 (DMAb-3876-FY)

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All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

This product is the plasmid containing an encoded anti-CD38 DMAb sequence. The plasmid can drive transcription and in vivo translation of the desired antibody.

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Specifications

  • Target
  • CD38
  • Vector Name
  • pVAX1
  • Vector Description
  • pVAX1 was originally designed for the development of DNA vaccines. Its eukaryotic DNA sequences limited to the expression of desired sequence so that minimize the possibility of chromosomal integration. This vector has been widely used for the construction of DMAb plasmid.
  • Vector Promoter
  • CMV
  • Vector Tag or Fusion
  • Untagged
  • Delivery Method
  • Transfection
  • Cloning Method
  • Restriction Enzyme ⁄ MCS
  • Constitutive or Inducible System
  • Constitutive
  • Storage
  • Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term.
  • Background
  • DNA-encoded mAb (DMAb) technology is a novel approach for a direct in vivo production of desired biologically active immunoglobulins according to the plasmid DNA delivery into tissue where the delivered plasmid containing an encoded antibody sequence. Compared with the traditional mAb, DMAb can be functionally equivalent with additional advantages such as expression profiles, glycosylation, as well as no reliance on in vivo tissue culture and costly or time-consuming production systems. The DMAb technology may provide a novel, simple, less frequent, cost-effective approach for therapeutics.

Target

Sub CAT. DMAb Clone DMAb Host Target Species DMAb Isotype DMAb Immunogen  
DMAb-3670CQ IB6 Mouse Human IgG2a
DMAb-3640CQ HIT2 Mouse Human IgG1 Human thymocytes in foetus
DMAb-3630CQ AT1 Mouse Human IgG1, κ Human T cell line CCRF-CEM
DMAb-3764CQ AT2 Mouse Human IgG3, κ Human T cell line CCRF-CEM
DMAb-3765CQ FS02 Mouse Human IgG1, κ Human CD38

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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