Anti-FOS DNA-encoded mAb (DMAb), pVAX1 (DMAb-1094-CQ)

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All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

This product is the plasmid containing an encoded anti-FOS DMAb sequence. The plasmid can drive transcription and in vivo translation of the desired antibody.

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Specifications

Target
FOS

Vector Name
pVAX1

Vector Description
pVAX1 was originally designed for the development of DNA vaccines. Its eukaryotic DNA sequences limited to the expression of desired sequence so that minimize the possibility of chromosomal integration. This vector has been widely used for the construction of DMAb plasmid.

Vector Promoter
CMV

Vector Tag or Fusion
Untagged

Delivery Method
Transfection

Cloning Method
Restriction Enzyme ⁄ MCS

Constitutive or Inducible System
Constitutive

Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term.

Background
DNA-encoded mAb (DMAb) technology is a novel approach for a direct in vivo production of desired biologically active immunoglobulins according to the plasmid DNA delivery into tissue where the delivered plasmid containing an encoded antibody sequence. Compared with the traditional mAb, DMAb can be functionally equivalent with additional advantages such as expression profiles, glycosylation, as well as no reliance on in vivo tissue culture and costly or time-consuming production systems. The DMAb technology may provide a novel, simple, less frequent, cost-effective approach for therapeutics.

Target

Entrez Gene ID
2353

UniProt ID
P01100

Sub CAT.	DMAb Clone	DMAb Host	Target Species	DMAb Isotype	DMAb Immunogen
DMAb-1095-CQ	G54-9.9	Mouse		IgG1
DMAb-429-YC	2G2	Mouse	Human	IgG1	Purified recombinant fragment of human FOS expressed in E. coli
DMAb-1101-CQ	8B5	Mouse		IgG1	Synthetic peptide corresponding to a portion of human c-Fos
DMAb-1108-CQ	3B8	Mouse	Human	IgG1
DMAb-1110-CQ	554C1a	Mouse	Human	IgG1
DMAb-1111-CQ	6A3	Mouse	Human	IgG
DMAb-427-YC	1E3	Mouse	Human	IgG1	Full length human recombinant protein of human FOS (NP_005243) expressed in E. coli
DMAb-1115-CQ	7D6	Mouse	Human	IgG1	Full length human recombinant protein of human FOS (NP_005243) expressed in E. coli
DMAb-1117-CQ	1H8	Mouse	Human	IgG2a, κ	Recombinant protein
DMAb-0772-WJ	A16-L	Rabbit		IgG	Peptide corresponding to the C-Terminus of human c-FOS

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

Anti-FOS DNA-encoded mAb (DMAb), pVAX1 (DMAb-1094-CQ)

Specifications

Target

Customer Reviews and Q&As

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