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Overview
Ewing sarcoma is a very rare form of cancerous bone tumor, which is consisted of three types and it arises primarily in bone or in soft tissue around bone—often the legs, pelvis, arms or spine. Ewing sarcoma can spread quickly to lungs, kidneys, heart, other bones and bone marrow. The disease cases are mostly found in teenagers, particularly Caucasian young males. Although it does not show to be inherited, the cause of Ewing sarcoma is genetic, chromosome changes, in a process known as translocation, chromosomes 11 and 22 exchange small fragment of each other. Normally, DNA assay can detect the abnormal gene.
Signs, symptoms and treatments
The symptoms of Ewing's sarcoma include swelling at the site fo the tumor, low fever, bone pain and weight loss, however, depending on the tumor size and whether or not the disease has spread, the signs will vary. Chemotherapy is usually to be the first step in treating Ewing sarcoma to shrink the tumor size so as to make sure the following surgery to be most effective.
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NEW SOLUTION
CellRapeutics™ In Vivo Cell Engineering: One-stop in vivo T/B/NK cell and macrophage engineering services covering vectors construction to function verification.
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NOVEL TECHNOLOGY
Silence™ CAR-T Cell: A novel platform to enhance CAR-T cell immunotherapy by combining RNAi technology to suppress genes that may impede CAR functionality.
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NEW SOLUTION
Canine CAR-T Therapy Development: From early target discovery, CAR design and construction, cell culture, and transfection, to in vitro and in vivo function validation.
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