Stem Cell Products

As a special cell type, stem cells have self-renewal and multi-directional differentiation potential. They can differentiate into different specialized cell types and perform special functions in the body, including but not limited to blood cells, brain cells, bone cells, and heart muscle cells. It is worth noting that stem cells hold immense potential for advancing medical treatments. Stem cell researches help us gain a deeper understanding of the development of diseases. For translational research, the multidirectional differentiation potential of stem cells can be utilized to further treat some damaging diseases. Furthermore, stem cells can be utilized in the testing of new drugs to assess their safety and efficacy. The multiple applications of stem cells in disease therapy hold great promise for the future.

Fig.1 Mesenchymal stem cells apply to regenerative medicine.¹

Categories of Stem Cells

• Embryonic Stem Cells (ESCs): ESCs are generated from embryos at an average developmental phase of 3 to 5 days. During this developmental phase, the developing organism is often referred to as a blastocyst. ESCs feature pluripotent, which means they may proliferate and convert into any kind of cell internal body. The remarkable adaptability of ESCs makes it possible for the use of stem cells in the rejuvenation or repair of damaged areas.
• Adult Stem Cells (ASCs): Undifferentiated ASCs have been identified inside differentiated tissues, demonstrating the capacity to undergo self-renewal and generate new cells that help with the repair of damaged or wounded tissue. ASCs can't generate as large a number of body cells as ESCs. Alternately, ASCs may differentiate into ESCs.
• Induced Pluripotent Stem Cells (iPSCs): iPSCs are generated by introducing embryonic genes into a somatic cell, which triggers its transformation into a state resembling that of a stem cell. Similar to ESCs, these cells are regarded as pluripotent. Moreover, iPSCs have an unlimited source, which avoids the requirement for embryos in stem cell therapy. Produced using the recipient's own cells, these autologous transplants provide no danger of immunological rejection.

Applications of Stem Cells

• Treatment Involving the Transfer of Hematopoietic Stem Cells (HSCs): Transplantation of multipotent HSCs is now the most frequently employed stem cell treatment. HSCs produce all blood cells, enabling the body to function normally. The process may be syngeneic, allogeneic, or autologous. Cancers derived from dysfunction of the hematopoietic system, such as leukemia and anemia, may be remedied by transplanting healthy HSCs.
• Pharmacological Examination Targets: Using certain differentiated cells derived from pluripotent cells to conduct live system treatment may be safer. Meanwhile, medication formulation optimization helps to reduce the occurrence of adverse reactions.
• Cell-based Treatment Options: The ability of stem cells to differentiate into various cell types is crucial for repairing and restoring damaged tissues. This approach allows for the creation of healthy heart muscle cells that can be subsequently transplanted into patients suffering from heart disease. Furthermore, the development of stem cells into cells that produce insulin serves as an alternative treatment for type 1 diabetes, instead of transplantation therapy.

Stem Cells at Creative Biolabs

In order to cater to the demands of our global customers and streamline the conversion of stem cell research into clinical applications, Creative Biolabs enthusiastically offers a diverse range of readily used stem cell products that have undergone rigorous quality assurance measures. Please don't hesitate to contact us and inquire about a suitable product.

Reference

1. Han, Yu, et al. "Mesenchymal stem cells for regenerative medicine." Cells 8 8 (2019): 886.