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LCP1

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Plastins are a family of actin-binding proteins that are conserved throughout eukaryote evolution and expressed in most tissues of higher eukaryotes. In humans, two ubiquitous plastin isoforms (L and T) have been identified. Plastin 1 (otherwise known as Fimbrin) is a third distinct plastin isoform which is specifically expressed at high levels in the small intestine. The L isoform is expressed only in hemopoietic cell lineages, while the T isoform has been found in all other normal cells of solid tissues that have replicative potential (fibroblasts, endothelial cells, epithelial cells, melanocytes, etc.). However, L-plastin has been found in many types of malignant human cells of non-hemopoietic origin suggesting that its expression is induced accompanying tumorigenesis in solid tissues. Among its related pathways are NF-kappaB Signaling. Gene Ontology (GO) annotations related to this gene include calcium ion binding and actin binding.
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CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type CAR Vector Type Inquiry & Datasheet
CAR-YJ051 Anti-LCP1 (LPL4A.1) h(41BB-CD3ζ) CAR, pCDCAR1 Human LPL4A.1 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-YJ551 Anti-LCP1 (LPL4A.1) h(CD28-CD3ζ) CAR, pCDCAR1 Human LPL4A.1 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-0320ZP1425 Anti-LCP1 (MQM5B.2) h(CD28-CD3ζ) CAR, pCDCAR1 Human MQM5B.2 Mouse scFv-CD28-CD3ζ Lentiviral vector T Cell   Add to Cart   Datasheet
CAR-0320ZP1426 Anti-LCP1 (MQM5B.2) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human MQM5B.2 Mouse scFv-4-1BB-CD3ζ Lentiviral vector T Cell   Add to Cart   Datasheet
CAR-0320ZP1427 Anti-LCP1 (D1C3) h(CD28-CD3ζ) CAR, pCDCAR1 Human D1C3 Rabbit scFv-CD28-CD3ζ Lentiviral vector T Cell   Add to Cart   Datasheet
CAR-0320ZP1428 Anti-LCP1 (D1C3) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human D1C3 Rabbit scFv-4-1BB-CD3ζ Lentiviral vector T Cell   Add to Cart   Datasheet
CAR-0320ZP1430 Anti-LCP1 (LPL4A.1) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human LPL4A.1 Mouse scFv-4-1BB-CD3ζ Lentiviral vector T Cell   Add to Cart   Datasheet
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