This product is an aptamer which binds to the Acute myeloid leukemia cells (HL60) with an affinity of <20 nM.
Target Category | Cell |
Target | Acute myeloid leukemia cells (HL60) |
Chemical Modification | DNA |
Length | 60-80 nt |
Affinity (Kd) | <20 nM |
Binding Conditions/Buffer | Binding Buffer (4.5 g/L glucose, 5 mM MgCl2, 0.1 mg/ml tRNA and 1mg/ml BSA, dissolved in Dulbecco's PBS with MgCl2 and CaCl2) containing 20% FBS. |
GC Content | 0.4706 |
Molecular Weight | 20896.62 g/mole |
Extinction Coefficient | 647700 L/(mole·cm) |
nmoles/OD260 | 1.54 |
The KH1C12 aptamer works greatExcellentIt has a strong binding site and provides consistent results in each setup. Its high specificity helps in isolating the target cells efficiently.
High specificity and good packagingExcellentI had previously used various reagents for my research, but the specificity I got with the KH1C12 aptamer has been unmatched.
Exceeded my expectationsExcellentI have had a positive experience utilizing the KH1C12 aptamer in my research. Its high perfomance and quality have helped me generate data with confidence.
Highly specific to AML cellsExcellentThe consistency and reliability of the KH1C12 aptamer in our experiments have been outstanding. It binds specifically to AML cells without cross-reacting with other cell types.