Acute myeloid leukemia cells Aptamer(Cat#: CTApt-282)

This product is an aptamer which binds to the Acute myeloid leukemia cells (HL60) with an affinity of <20 nM.

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3’ Modification
 
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Specifications
Target Category Cell
Target Acute myeloid leukemia cells (HL60)
Chemical Modification DNA
Length 60-80 nt
Affinity (Kd) <20 nM
Binding Conditions/Buffer Binding Buffer (4.5 g/L glucose, 5 mM MgCl2, 0.1 mg/ml tRNA and 1mg/ml BSA, dissolved in Dulbecco's PBS with MgCl2 and CaCl2) containing 20% FBS.
GC Content 0.4706
Molecular Weight 20896.62 g/mole
Extinction Coefficient 647700 L/(mole·cm)
nmoles/OD260 1.54

Customer Review

The KH1C12 aptamer works great
Excellent
It has a strong binding site and provides consistent results in each setup. Its high specificity helps in isolating the target cells efficiently.
High specificity and good packaging
Excellent
I had previously used various reagents for my research, but the specificity I got with the KH1C12 aptamer has been unmatched.
Exceeded my expectations
Excellent
I have had a positive experience utilizing the KH1C12 aptamer in my research. Its high perfomance and quality have helped me generate data with confidence.
Highly specific to AML cells
Excellent
The consistency and reliability of the KH1C12 aptamer in our experiments have been outstanding. It binds specifically to AML cells without cross-reacting with other cell types.
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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