This is an aptamer development services to screening aptamers binds to the ABCB8 with an affinity of 1nM~1μM.
Target Category | Protein |
Target | ABCB8 |
Alternative Names | ATP Binding Cassette Subfamily B Member 8; MITOSUR; M-ABC1; MABC1; ATP-Binding Cassette Sub-Family B Member 8, Mitochondrial; ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 8; Mitochondrial Potassium Channel ATP-Binding Subunit; Mitochondrial ATP-Binding Cassette 1; Mitochondrial Sulfonylurea-Receptor; Mitochondrial ABC Protein; EST328128; EC 3.6.3; ABCB8 |
Gene ID | 11194 |
UniProt ID | Q9NUT2 |
Target Overview | This nuclear gene encodes a multi-pass membrane protein that is targeted to the mitochondrial inner membrane. The encoded protein is an ATP-dependent transporter that may mediate the passage of organic and inorganic molecules out of the mitochondria. Loss of function of the related gene in mouse results in a disruption of iron homeostasis between the mitochondria and cytosol. Alternative splicing results in multiple transcript variants. |
Chemical Modification | N/A |
Type | DNA |
Length | 20-80 nt |
Affinity (Kd) | 1nM~1μM |
Binding Conditions/Buffer | PBS; buffer system with Serum; other |