This is an aptamer development services to screening aptamers binds to the ACER2 with an affinity of 1nM~1μM.
Target Category | Protein |
Target | ACER2 |
Alternative Names | Alkaline Ceramidase 2; N-Acylsphingosine Amidohydrolase 3-Like; Alkaline CDase 2; AlkCDase 2; ALKCDase2; ASAH3L; HaCER2; Acylsphingosine Deacylase 3-Like; Ceramide Hydrolase; EC 3.5.1.23; EC 3.5.1.- ; FLJ41587; ACER2 |
Gene ID | 340485 |
UniProt ID | Q5QJU3 |
Target Overview | The sphingolipid metabolite sphingosine-1-phosphate promotes cell proliferation and survival, whereas its precursor, sphingosine, has the opposite effect. The ceramidase ACER2 hydrolyzes very long chain ceramides to generate sphingosine (Xu et al., 2006 [PubMed 16940153]). |
Chemical Modification | N/A |
Type | DNA |
Length | 20-80 nt |
Affinity (Kd) | 1nM~1μM |
Binding Conditions/Buffer | PBS; buffer system with Serum; other |