Anti-ACTL6A aptamer SELEX Service(Cat#: CTApt-1651)
This is an aptamer development services to screening aptamers binds to the ACTL6A with an affinity of 1nM~1μM.
Specific Inquiry 
Summary
Specifications
| Target Category |
Protein |
| Target |
ACTL6A |
| Alternative Names |
Actin Like 6A; BRG1-Associated Factor 53A; INO80 Complex Subunit K; BAF53A; INO80K; 53 KDa BRG1-Associated Factor A; Actin-Related Protein Baf53a; BAF Complex 53 KDa Subunit; Actin-Related Protein 4; Actin-Like Protein 6A; ArpNbeta; BAF53; Arp4; HArpN Beta; ARPN-BETA; ACTL6A; Baf53a; ACTL6; Actl6 |
| Gene ID |
86 |
| UniProt ID |
O96019 |
| Target Overview |
This gene encodes a family member of actin-related proteins (ARPs), which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene encodes a 53 kDa subunit protein of the BAF (BRG1/brm-associated factor) complex in mammals, which is functionally related to SWI/SNF complex in S. cerevisiae and Drosophila; the latter is thought to facilitate transcriptional activation of specific genes by antagonizing chromatin-mediated transcriptional repression. Together with beta-actin, it is required for maximal ATPase activity of BRG1, and for the association of the BAF complex with chromatin/matrix. Three transcript variants that encode two different protein isoforms have been described. |
| Chemical Modification |
N/A |
| Type |
DNA |
| Length |
20-80 nt |
| Affinity (Kd) |
1nM~1μM |
| Binding Conditions/Buffer |
PBS; buffer system with Serum; other |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
