Anti-ACVR1C Aptamer SELEX Service(Cat#: CTApt-994)
This is an aptamer development services to screening aptamers binds to the ACVR1C with an affinity of 1nM~1μM.
Specific Inquiry 
Summary
Specifications
| Target Category |
Protein |
| Target |
ACVR1C |
| Alternative Names |
Activin A Receptor Type 1C; ALK7; Activin Receptor-Like Kinase 7; Activin A Receptor, Type IC; Activin Receptor Type-1C; Activin Receptor Type IC; EC 2.7.11.30; ACVRLK7; ACTR-IC; ALK-7; EC 2.7.11; ACVR1C |
| Gene ID |
130399 |
| UniProt ID |
Q8NER5 |
| Target Overview |
ACVR1C is a type I receptor for the TGFB (see MIM 190180) family of signaling molecules. Upon ligand binding, type I receptors phosphorylate cytoplasmic SMAD transcription factors, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors (Bondestam et al., 2001 [PubMed 12063393]). |
| Chemical Modification |
N/A |
| Type |
DNA |
| Length |
20-80 nt |
| Affinity (Kd) |
1nM~1μM |
| Binding Conditions/Buffer |
PBS; buffer system with Serum; other |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
