This is an aptamer development services to screening aptamers binds to the ADAM10 with an affinity of 1nM~1μM.
Target Category | Protein |
Target | ADAM10 |
Alternative Names | ADAM Metallopeptidase Domain 10; MADM; Disintegrin And Metalloproteinase Domain-Containing Protein 10; Mammalian Disintegrin-Metalloprotease; Kuzbanian Protein Homolog; EC 3.4.24.81; HsT18717; CDw156; Kuz; A Disintegrin And Metalloproteinase Domain 10; A Disintegrin And Metalloprotease Domain 10; CD156c Antigen; EC 3.4.24; ADAM 10; CD156c; ADAM10; CD156C; AD10; AD18; RAK; KUZ |
Gene ID | 102 |
UniProt ID | O14672 |
Target Overview | Members of the ADAM family are cell surface proteins with a unique structure possessing both potential adhesion and protease domains. This gene encodes and ADAM family member that cleaves many proteins including TNF-alpha and E-cadherin. Alternate splicing results in multiple transcript variants encoding different proteins that may undergo similar processing. |
Chemical Modification | N/A |
Type | DNA |
Length | 20-80 nt |
Affinity (Kd) | 1nM~1μM |
Binding Conditions/Buffer | PBS; buffer system with Serum; other |