This is an aptamer development services to screening aptamers binds to the ADAM19 with an affinity of 1nM~1μM.
Target Category | Protein |
Target | ADAM19 |
Alternative Names | ADAM Metallopeptidase Domain 19; MLTNB; Disintegrin And Metalloproteinase Domain-Containing Protein 19; A Disintegrin And Metalloproteinase Domain 19 (Meltrin Beta) ; Metalloprotease And Disintegrin Dendritic Antigen Marker; MADDAM; Metalloprotease-Disintegrin Meltrin Beta; Meltrin Beta; Meltrin-Beta; EC 3.4.24.- ; EC 3.4.24; ADAM 19; FKSG34; ADAM19 |
Gene ID | 8728 |
UniProt ID | Q9H013 |
Target Overview | This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This member is a type I transmembrane protein and serves as a marker for dendritic cell differentiation. It has been demonstrated to be an active metalloproteinase, which may be involved in normal physiological processes such as cell migration, cell adhesion, cell-cell and cell-matrix interactions, and signal transduction. It is proposed to play a role in pathological processes, such as cancer, inflammatory diseases, renal diseases, and Alzheimer's disease. |
Chemical Modification | N/A |
Type | DNA |
Length | 20-80 nt |
Affinity (Kd) | 1nM~1μM |
Binding Conditions/Buffer | PBS; buffer system with Serum; other |