Anti-ADAM19 Aptamer SELEX Service(Cat#: CTApt-2479)

This is an aptamer development services to screening aptamers binds to the ADAM19 with an affinity of 1nM~1μM.

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5’ Modification
 
3’ Modification
 
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Summary

Specifications
Target Category Protein
Target ADAM19
Alternative Names ADAM Metallopeptidase Domain 19; MLTNB; Disintegrin And Metalloproteinase Domain-Containing Protein 19; A Disintegrin And Metalloproteinase Domain 19 (Meltrin Beta) ; Metalloprotease And Disintegrin Dendritic Antigen Marker; MADDAM; Metalloprotease-Disintegrin Meltrin Beta; Meltrin Beta; Meltrin-Beta; EC 3.4.24.- ; EC 3.4.24; ADAM 19; FKSG34; ADAM19
Gene ID 8728
UniProt ID Q9H013
Target Overview This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This member is a type I transmembrane protein and serves as a marker for dendritic cell differentiation. It has been demonstrated to be an active metalloproteinase, which may be involved in normal physiological processes such as cell migration, cell adhesion, cell-cell and cell-matrix interactions, and signal transduction. It is proposed to play a role in pathological processes, such as cancer, inflammatory diseases, renal diseases, and Alzheimer's disease.
Chemical Modification N/A
Type DNA
Length 20-80 nt
Affinity (Kd) 1nM~1μM
Binding Conditions/Buffer PBS; buffer system with Serum; other
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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