This is an aptamer development services to screening aptamers binds to the ADAMTS3 with an affinity of 1nM~1μM.
Target Category | Protein |
Target | ADAMTS3 |
Alternative Names | ADAM Metallopeptidase With Thrombospondin Type 1 Motif 3; A Disintegrin-Like And Metalloprotease (Reprolysin Type) With Thrombospondin Type 1 Motif, 3; A Disintegrin And Metalloproteinase With Thrombospondin Motifs 3; Procollagen II Amino Propeptide-Processing Enzyme; Procollagen II N-Proteinase; ADAM-TS 3; ADAMTS-4; ADAM-TS3; ADAMTS-3; PC II-NP; KIAA0366; Zinc Metalloendopeptidase; EC 3.4.24.14; EC 3.4.24.- ; EC 3.4.24; ADAMTS3; HKLLS3 |
Gene ID | 9508 |
UniProt ID | O15072 |
Target Overview | This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature protease. This protease, a member of the procollagen aminopropeptidase subfamily of proteins, may play a role in the processing of type II fibrillar collagen in articular cartilage. |
Chemical Modification | N/A |
Type | DNA |
Length | 20-80 nt |
Affinity (Kd) | 1nM~1μM |
Binding Conditions/Buffer | PBS; buffer system with Serum; other |