Anti-ADRA1B Aptamer SELEX Service(Cat#: CTApt-2447)
This is an aptamer development services to screening aptamers binds to the ADRA1B with an affinity of 1nM~1μM.
Specific Inquiry 
Summary
Specifications
| Target Category |
Protein |
| Target |
ADRA1B |
| Alternative Names |
Adrenoceptor Alpha 1B; Adrenergic, Alpha-1B-, Receptor; Alpha-1B Adrenergic Receptor; Alpha-1B Adrenoreceptor; Alpha-1B Adrenoceptor; ALPHA1BAR; ADRA1B; ADRA1 |
| Gene ID |
147 |
| UniProt ID |
P35368 |
| Target Overview |
Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1B-adrenergic receptor, which induces neoplastic transformation when transfected into NIH 3T3 fibroblasts and other cell lines. Thus, this normal cellular gene is identified as a protooncogene. This gene comprises 2 exons and a single large intron of at least 20 kb that interrupts the coding region. |
| Chemical Modification |
N/A |
| Type |
DNA |
| Length |
20-80 nt |
| Affinity (Kd) |
1nM~1μM |
| Binding Conditions/Buffer |
PBS; buffer system with Serum; other |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
