This is an aptamer development services to screening aptamers binds to the AGPS with an affinity of 1nM~1μM.
Target Category | Protein |
Target | AGPS |
Alternative Names | Alkylglycerone Phosphate Synthase; Alkyldihydroxyacetonephosphate Synthase, Peroxisomal; Aging-Associated Gene 5 Protein; Alkyl-DHAP Synthase; EC 2.5.1.26; ALDHPSY; ADAP-S; ADHAPS; ADAS; ADPS; Alkylglycerone-Phosphate Synthase; Aging-Associated Protein 5; RCDP3; AGPS |
Gene ID | 8540 |
UniProt ID | O00116 |
Target Overview | This gene is a member of the FAD-binding oxidoreductase/transferase type 4 family. It encodes a protein that catalyzes the second step of ether lipid biosynthesis in which acyl-dihydroxyacetonephosphate (DHAP) is converted to alkyl-DHAP by the addition of a long chain alcohol and the removal of a long-chain acid anion. The protein is localized to the inner aspect of the peroxisomal membrane and requires FAD as a cofactor. Mutations in this gene have been associated with rhizomelic chondrodysplasia punctata, type 3 and Zellweger syndrome. |
Chemical Modification | N/A |
Type | DNA |
Length | 20-80 nt |
Affinity (Kd) | 1nM~1μM |
Binding Conditions/Buffer | PBS; buffer system with Serum; other |