Anti-AKR1C1 Aptamer SELEX Service(Cat#: CTApt-2444)
This is an aptamer development services to screening aptamers binds to the AKR1C1 with an affinity of 1nM~1μM.
Specific Inquiry 
Summary
Specifications
| Target Category |
Protein |
| Target |
AKR1C1 |
| Alternative Names |
Aldo-Keto Reductase Family 1 Member C1; DDH; Dihydrodiol Dehydrogenase 1; 20-Alpha (3-Alpha)-Hydroxysteroid Dehydrogenase; High-Affinity Hepatic Bile Acid-Binding Protein; Trans-1,2-Dihydrobenzene-1,2-Diol Dehydrogenase; Chlordecone Reductase Homolog HAKRC; Dihydrodiol Dehydrogenase 1/2; Indanol Dehydrogenase; DD1/DD2; HAKRC; DDH1; HBAB; MBAB; DD1; Aldo-Keto Reductase Family 1, Member C1 (Dihydrodiol Dehydrogenase 1; 20-Alpha (3-Alpha)-Hydroxysteroid Dehydrogenase) ; Type II 3-Alpha-Hydroxysteroid Dehydrogenase; 20 Alpha-Hydroxysteroid Dehydrogenase; Dihydrodiol Dehydrogenase Isoform DD1; 20-Alpha-Hydroxysteroid Dehydrogenase; Hepatic Dihydrodiol Dehydrogenase; Dihydrodiol Dehydrogenase 1; Aldo-Keto Reductase C; 20-ALPHA-HSD; 20-Alpha-HSD; EC 1.1.1.149; EC 1.1.1.112; 2-ALPHA-HSD; EC 1.3.1.20; EC 1.1.1.- ; EC 1.1.1; AKR1C1; H-37; C9 |
| Gene ID |
1645 |
| UniProt ID |
Q04828 |
| Target Overview |
This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reaction of progesterone to the inactive form 20-alpha-hydroxy-progesterone. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. |
| Chemical Modification |
N/A |
| Type |
DNA |
| Length |
20-80 nt |
| Affinity (Kd) |
1nM~1μM |
| Binding Conditions/Buffer |
PBS; buffer system with Serum; other |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
