This is an aptamer development services to screening aptamers binds to the ANGPTL4 with an affinity of 1nM~1μM.
Target Category | Protein |
Target | ANGPTL4 |
Alternative Names | Angiopoietin Like 4; Hepatic Fibrinogen/Angiopoietin-Related Protein; Angiopoietin-Related Protein 4; HFARP; ARP4; PGAR; Peroxisome Proliferator-Activated Receptor (PPAR) Gamma Induced Angiopoietin-Related Protein; Hepatic Angiopoietin-Related Protein; PPARG Angiopoietin Related Protein; Fasting-Induced Adipose Factor; Pp1158; FIAF; NL2; Angiopoietin-Like Protein 4; Angiopoietin-Like 4; ANGPTL4; UNQ171; TGQTL; HARP |
Gene ID | 51129 |
UniProt ID | Q9BY76 |
Target Overview | This gene encodes a glycosylated, secreted protein containing a C-terminal fibrinogen domain. The encoded protein is induced by peroxisome proliferation activators and functions as a serum hormone that regulates glucose homeostasis, lipid metabolism, and insulin sensitivity. This protein can also act as an apoptosis survival factor for vascular endothelial cells and can prevent metastasis by inhibiting vascular growth and tumor cell invasion. The C-terminal domain may be proteolytically-cleaved from the full-length secreted protein. Decreased expression of this gene has been associated with type 2 diabetes. Alternative splicing results in multiple transcript variants. This gene was previously referred to as ANGPTL2 but has been renamed ANGPTL4. |
Chemical Modification | N/A |
Type | DNA |
Length | 20-80 nt |
Affinity (Kd) | 1nM~1μM |
Binding Conditions/Buffer | PBS; buffer system with Serum; other |