Anti-APBA1 Aptamer SELEX Service(Cat#: CTApt-2499)
This is an aptamer development services to screening aptamers binds to the APBA1 with an affinity of 1nM~1μM.
Specific Inquiry 
Summary
Specifications
| Target Category |
Protein |
| Target |
APBA1 |
| Alternative Names |
Amyloid Beta Precursor Protein Binding Family A Member 1; X11; Amyloid-Beta A4 Precursor Protein-Binding Family A Member 1; Neuronal Munc18-1-Interacting Protein 1; Neuron-Specific X11 Protein; Adapter Protein X11alpha; D9S411E; Mint-1; MINT1; Amyloid Beta (A4) Precursor Protein-Binding, Family A, Member 1 (X11) ; Phosphotyrosine-Binding/-Interacting Domain (PTB)-Bearing Protein; Amyloid Beta (A4) Precursor Protein-Binding, Family A, Member 1; Adaptor Protein X11alpha; X11ALPHA; LIN10; APBA1; X11A |
| Gene ID |
320 |
| UniProt ID |
Q02410 |
| Target Overview |
The protein encoded by this gene is a member of the X11 protein family. It is a neuronal adapter protein that interacts with the Alzheimer's disease amyloid precursor protein (APP). It stabilizes APP and inhibits production of proteolytic APP fragments including the A beta peptide that is deposited in the brains of Alzheimer's disease patients. This gene product is believed to be involved in signal transduction processes. It is also regarded as a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion. |
| Chemical Modification |
N/A |
| Type |
DNA |
| Length |
20-80 nt |
| Affinity (Kd) |
1nM~1μM |
| Binding Conditions/Buffer |
PBS; buffer system with Serum; other |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
