Anti-APEH Aptamer SELEX Service(Cat#: CTApt-2109)
This is an aptamer development services to screening aptamers binds to the APEH with an affinity of 1nM~1μM.
Specific Inquiry 
Summary
Specifications
| Target Category |
Protein |
| Target |
APEH |
| Alternative Names |
Acylaminoacyl-Peptide Hydrolase; Acylamino-Acid-Releasing Enzyme; Acylaminoacyl-Peptidase; N-Acylaminoacyl-Peptide Hydrolase; Oxidized Protein Hydrolase; Acyl-Peptide Hydrolase; EC 3.4.19.1; D3F15S2; DNF15S2; D3S48E; AARE; APH; OPH; ACPH; APEH |
| Gene ID |
327 |
| UniProt ID |
P13798 |
| Target Overview |
This gene encodes the enzyme acylpeptide hydrolase, which catalyzes the hydrolysis of the terminal acetylated amino acid preferentially from small acetylated peptides. The acetyl amino acid formed by this hydrolase is further processed to acetate and a free amino acid by an aminoacylase. This gene is located within the same region of chromosome 3 (3p21) as the aminoacylase gene, and deletions at this locus are also associated with a decrease in aminoacylase activity. The acylpeptide hydrolase is a homotetrameric protein of 300 kDa with each subunit consisting of 732 amino acid residues. It can play an important role in destroying oxidatively damaged proteins in living cells. Deletions of this gene locus are found in various types of carcinomas, including small cell lung carcinoma and renal cell carcinoma. |
| Chemical Modification |
N/A |
| Type |
DNA |
| Length |
20-80 nt |
| Affinity (Kd) |
1nM~1μM |
| Binding Conditions/Buffer |
PBS; buffer system with Serum; other |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
