This is an aptamer development services to screening aptamers binds to the ARAP1 with an affinity of 1nM~1μM.
Target Category | Protein |
Target | ARAP1 |
Alternative Names | ArfGAP With RhoGAP Domain, Ankyrin Repeat And PH Domain 1; Arf-GAP With Rho-GAP Domain, ANK Repeat And PH Domain-Containing Protein 1; Centaurin-Delta-2; CENTD2; Cnt-D2; ARF-GAP, RHO-GAP, Ankyrin Repeat, And Pleckstrin Homology Domains-Containing Protein ; Centaurin, Delta 2; KIAA0782; ARAP1 |
Gene ID | 116985 |
UniProt ID | Q96P48 |
Target Overview | The protein encoded by this gene contains SAM, ARF-GAP, RHO-GAP, ankyrin repeat, RAS-associating, and pleckstrin homology (PH) domains. In vitro, this protein displays RHO-GAP and phosphatidylinositol (3,4,5) trisphosphate (PIP3)-dependent ARF-GAP activity. The encoded protein associates with the Golgi, and the ARF-GAP activity mediates changes in the Golgi and the formation of filopodia. It is thought to regulate the cell-specific trafficking of a receptor protein involved in apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene. |
Chemical Modification | N/A |
Type | DNA |
Length | 20-80 nt |
Affinity (Kd) | 1nM~1μM |
Binding Conditions/Buffer | PBS; buffer system with Serum; other |