Anti-ARID4A Aptamer SELEX Service(Cat#: CTApt-1195)
This is an aptamer development services to screening aptamers binds to the ARID4A with an affinity of 1nM~1μM.
Specific Inquiry 
Summary
Specifications
| Target Category |
Protein |
| Target |
ARID4A |
| Alternative Names |
AT-Rich Interaction Domain 4A; Retinoblastoma-Binding Protein 1; RBP1; AT-Rich Interactive Domain-Containing Protein 4A; AT Rich Interactive Domain 4A (RBP1-Like) ; ARID Domain-Containing Protein 4A; RBBP-1; RBBP1; RBP-1; ARID4A |
| Gene ID |
5926 |
| UniProt ID |
P29374 |
| Target Overview |
The protein encoded by this gene is a ubiquitously expressed nuclear protein. It binds directly, with several other proteins, to retinoblastoma protein (pRB) which regulates cell proliferation. pRB represses transcription by recruiting the encoded protein. This protein, in turn, serves as a bridging molecule to recruit HDACs and, in addition, provides a second HDAC-independent repression function. The encoded protein possesses transcriptional repression activity. Multiple alternatively spliced transcripts have been observed for this gene, although not all transcript variants have been fully described. |
| Chemical Modification |
N/A |
| Type |
DNA |
| Length |
20-80 nt |
| Affinity (Kd) |
1nM~1μM |
| Binding Conditions/Buffer |
PBS; buffer system with Serum; other |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
