Anti-ARNTL2 Aptamer SELEX Service(Cat#: CTApt-1193)
This is an aptamer development services to screening aptamers binds to the ARNTL2 with an affinity of 1nM~1μM.
Specific Inquiry 
Summary
Specifications
| Target Category |
Protein |
| Target |
ARNTL2 |
| Alternative Names |
Aryl Hydrocarbon Receptor Nuclear Translocator Like 2; BHLHe6; BMAL2; PASD9; CLIF; MOP9; Aryl Hydrocarbon Receptor Nuclear Translocator-Like Protein 2; Class E Basic Helix-Loop-Helix Protein 6; Basic-Helix-Loop-Helix-PAS Protein MOP9; PAS Domain-Containing Protein 9; Brain And Muscle ARNT-Like 2; Member Of PAS Protein 9; CYCLE-Like Factor; Transcription Factor BMAL2; ARNTL2; BHLHE6 |
| Gene ID |
56938 |
| UniProt ID |
Q8WYA1 |
| Target Overview |
This gene encodes a basic helix-loop-helix transcription factor belonging to the PAS (PER, ARNT, SIM) superfamily. The PAS proteins play important roles in adaptation to low atmospheric and cellular oxygen levels, exposure to certain environmental pollutants, and diurnal oscillations in light and temperature. This protein forms a transcriptionally active heterodimer with the circadian CLOCK protein, the structurally related MOP4, and hypoxia-inducible factors, such as HIF1alpha. Consistent with its role as a biologically relevant partner of circadian and hypoxia factors, this protein is coexpressed in regions of the brain such as the thalamus, hypothalamus, and amygdala. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. |
| Chemical Modification |
N/A |
| Type |
DNA |
| Length |
20-80 nt |
| Affinity (Kd) |
1nM~1μM |
| Binding Conditions/Buffer |
PBS; buffer system with Serum; other |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
