Anti-ASGR1 Aptamer SELEX Service(Cat#: CTApt-2222)
This is an aptamer development services to screening aptamers binds to the ASGR1 with an affinity of 1nM~1μM.
Specific Inquiry 
Summary
Specifications
| Target Category |
Protein |
| Target |
ASGR1 |
| Alternative Names |
Asialoglycoprotein Receptor 1; CLEC4H1; C-Type Lectin Domain Family 4 Member H1; Hepatic Lectin H1; HL-1; ASGP-R 1; ASGPR 1; ASGPR; ASGPR; ASGR1 |
| Gene ID |
432 |
| UniProt ID |
P07306 |
| Target Overview |
This gene encodes a subunit of the asialoglycoprotein receptor. This receptor is a transmembrane protein that plays a critical role in serum glycoprotein homeostasis by mediating the endocytosis and lysosomal degradation of glycoproteins with exposed terminal galactose or N-acetylgalactosamine residues. The asialoglycoprotein receptor may facilitate hepatic infection by multiple viruses including hepatitis B, and is also a target for liver-specific drug delivery. The asialoglycoprotein receptor is a hetero-oligomeric protein composed of major and minor subunits, which are encoded by different genes. The protein encoded by this gene is the more abundant major subunit. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. |
| Chemical Modification |
N/A |
| Type |
DNA |
| Length |
20-80 nt |
| Affinity (Kd) |
1nM~1μM |
| Binding Conditions/Buffer |
PBS; buffer system with Serum; other |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
