This is an aptamer development services to screening aptamers binds to the ATP5PD with an affinity of 1nM~1μM.
Target Category | Protein |
Target | ATP5PD |
Alternative Names | ATP Synthase Peripheral Stalk Subunit D; ATP Synthase, H+ Transporting, Mitochondrial F0 Complex, Subunit D; ATP Synthase, H+ Transporting, Mitochondrial Fo Complex, Subunit D; ATP Synthase, H+ Transporting, Mitochondrial Fo Complex Subunit D; ATP Synthase Subunit D, Mitochondrial; ATPase Subunit D; ATP5H; ATPQ; ATP Synthase, H+ Transporting, Mitochondrial F1F0, Subunit D; ATP Synthase D Chain, Mitochondrial; My032 Protein; ATP5PD; ATP5JD; APT5H |
Gene ID | 10476 |
UniProt ID | O75947 |
Target Overview | Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. It is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, which comprises the proton channel. The F1 complex consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled in a ratio of 3 alpha, 3 beta, and a single representative of the other 3. The Fo seems to have nine subunits (a, b, c, d, e, f, g, F6 and 8). This gene encodes the d subunit of the Fo complex. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. In addition, three pseudogenes are located on chromosomes 9, 12 and 15. |
Chemical Modification | N/A |
Type | DNA |
Length | 20-80 nt |
Affinity (Kd) | 1nM~1μM |
Binding Conditions/Buffer | PBS; buffer system with Serum; other |