This is an aptamer development services to screening aptamers binds to the ATP6V0A2 with an affinity of 1nM~1μM.
Target Category | Protein |
Target | ATP6V0A2 |
Alternative Names | ATPase H+ Transporting V0 Subunit A2; ATPase, H+ Transporting, Lysosomal V0 Subunit A2; TJ6; Lysosomal H(+)-Transporting ATPase V0 Subunit A2; V-Type Proton ATPase 116 KDa Subunit A; ATP6N1D; J6B7; TJ6M; A2; Vacuolar Proton Translocating ATPase 116 KDa Subunit A Isoform ; ATPase, H+ Transporting, Lysosomal V0 Subunit A Isoform 2; Vacuolar Proton Translocating ATPase 116 KDa Subunit A; V-Type Proton ATPase 116 KDa Subunit A Isoform 2; V-Type Proton ATPase 116 KDa Subunit A2; Infantile Malignant Osteopetrosis; Regeneration And Tolerance Factor; V-ATPase 116 KDa Subunit A2; V-ATPase 116 KDa; A2V-ATPase; ATP6V0A2; ARCL2A; ATP6A2; ATP6a2; ARCL; STV1; TJ6S; VPH1; TJ6s; Vph1; Stv1; RTF; WSS |
Gene ID | 23545 |
UniProt ID | Q9Y487 |
Target Overview | The protein encoded by this gene is a subunit of the vacuolar ATPase (v-ATPase), an heteromultimeric enzyme that is present in intracellular vesicles and in the plasma membrane of specialized cells, and which is essential for the acidification of diverse cellular components. V-ATPase is comprised of a membrane peripheral V(1) domain for ATP hydrolysis, and an integral membrane V(0) domain for proton translocation. The subunit encoded by this gene is a component of the V(0) domain. Mutations in this gene are a cause of both cutis laxa type II and wrinkly skin syndrome. |
Chemical Modification | N/A |
Type | DNA |
Length | 20-80 nt |
Affinity (Kd) | 1nM~1μM |
Binding Conditions/Buffer | PBS; buffer system with Serum; other |