Anti-ATP6V1A Aptamer SELEX Service(Cat#: CTApt-1192)
This is an aptamer development services to screening aptamers binds to the ATP6V1A with an affinity of 1nM~1μM.
Specific Inquiry 
Summary
Specifications
| Target Category |
Protein |
| Target |
ATP6V1A |
| Alternative Names |
ATPase H+ Transporting V1 Subunit A; ATPase, H+ Transporting, Lysosomal 70kDa, V1 Subunit A; V-Type Proton ATPase Catalytic Subunit A; Vacuolar Proton Pump Subunit Alpha; Vacuolar ATPase Isoform VA68; V-ATPase Subunit A; ATP6V1A1; ATP6A1; VA68; VPP2; Vma1; ATPase, H+ Transporting, Lysosomal (Vacuolar Proton Pump), Alpha Polypeptide, 70kD, Isoform 1; Vacuolar ATP Synthase Catalytic Subunit A, Ubiquitous Isoform; H+-Transporting ATPase Chain A, Vacuolar (VA68 Type) ; ATPase, H+ Transporting, Lysosomal, Subunit A1; H(+)-Transporting Two-Sector ATPase, Subunit A; Vacuolar Proton Pump Alpha Subunit 1; V-ATPase 69 KDa Subunit ; V-ATPase 69 KDa Subunit; V-ATPase A Subunit 1; EC 3.6.3.14; EC 7.1.2.2; EC 3.6.3; ATP6V1A; ARCL2D; IECEE3; HO68 |
| Gene ID |
523 |
| UniProt ID |
P38606 |
| Target Overview |
This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c", and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is one of two V1 domain A subunit isoforms and is found in all tissues. Transcript variants derived from alternative polyadenylation exist. |
| Chemical Modification |
N/A |
| Type |
DNA |
| Length |
20-80 nt |
| Affinity (Kd) |
1nM~1μM |
| Binding Conditions/Buffer |
PBS; buffer system with Serum; other |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
