Anti-ATP6V1G3 Aptamer SELEX Service (CTApt-1286)

Specifications

Target Category	Protein
Target	ATP6V1G3
Alternative Names	ATPase H+ Transporting V1 Subunit G3; ATP6G3; ATPase, H+ Transporting, Lysosomal 13kDa, V1 Subunit G3; V-Type Proton ATPase Subunit G 3; Vacuolar Proton Pump Subunit G 3; V-ATPase 13 KDa Subunit 3; V-ATPase Subunit G 3; Vma10; ATPase, H+ Transporting, Lysosomal (Vacuolar Proton Pump) Subunit G3; ATPase, H+ Transporting, Lysosomal 13kDa, V1 Subunit G Isoform ; ATPase, H+ Transporting, Lysosomal 13kD, V1 Subunit G Isoform 3; Vacuolar ATP Synthase Subunit G 3; Vacuolar Proton Pump G Subunit 3; Vacuolar Proton Pump, Subunit G3; V-ATPase G Subunit 3; V-ATPase G3 Subunit; ATP6V1G3
Gene ID	127124
UniProt ID	Q96LB4
Target Overview	This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c'' and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This gene encodes one of three G subunit proteins. Transcript variants encoding different isoforms have been found for this gene.
Chemical Modification	N/A
Type	DNA
Length	20-80 nt
Affinity (Kd)	1nM~1μM
Binding Conditions/Buffer	PBS; buffer system with Serum; other

Anti-ATP6V1G3 Aptamer SELEX Service(Cat#: CTApt-1286)