Anti-AURKA Aptamer SELEX Service(Cat#: CTApt-2304)

This is an aptamer development services to screening aptamers binds to the AURKA with an affinity of 1nM~1μM.

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Size
5’ Modification
 
3’ Modification
 
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Summary

Specifications
Target Category Protein
Target AURKA
Alternative Names Aurora Kinase A; ARK1; BTAK; AIK; Protein Phosphatase 1, Regulatory Subunit 47; Serine/Threonine-Protein Kinase Aurora-A; Serine/Threonine-Protein Kinase 6; Breast Tumor-Amplified Kinase; Aurora/IPL1-Related Kinase 1; Aurora 2; PPP1R47; STK15; AURA; STK6; STK7; Serine/Threonine Protein Kinase 15; Serine/Threonine-Protein Kinase 15; Serine/Threonine Kinase 1; Serine/Threonine Kinase 6; Aurora/IPL1-Like Kinase; Aurora-Related Kinase 1; Aurora-A Kinase; EC 2.7.11.1; AURKA; AIRK1; ARK-1; HARK1; AurA; AYK1; IAK1
Gene ID 6790
UniProt ID O14965
Target Overview The protein encoded by this gene is a cell cycle-regulated kinase that appears to be involved in microtubule formation and/or stabilization at the spindle pole during chromosome segregation. The encoded protein is found at the centrosome in interphase cells and at the spindle poles in mitosis. This gene may play a role in tumor development and progression. A processed pseudogene of this gene has been found on chromosome 1, and an unprocessed pseudogene has been found on chromosome 10. Multiple transcript variants encoding the same protein have been found for this gene.
Chemical Modification N/A
Type DNA
Length 20-80 nt
Affinity (Kd) 1nM~1μM
Binding Conditions/Buffer PBS; buffer system with Serum; other
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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