This is an aptamer development services to screening aptamers binds to the AURKA with an affinity of 1nM~1μM.
Target Category | Protein |
Target | AURKA |
Alternative Names | Aurora Kinase A; ARK1; BTAK; AIK; Protein Phosphatase 1, Regulatory Subunit 47; Serine/Threonine-Protein Kinase Aurora-A; Serine/Threonine-Protein Kinase 6; Breast Tumor-Amplified Kinase; Aurora/IPL1-Related Kinase 1; Aurora 2; PPP1R47; STK15; AURA; STK6; STK7; Serine/Threonine Protein Kinase 15; Serine/Threonine-Protein Kinase 15; Serine/Threonine Kinase 1; Serine/Threonine Kinase 6; Aurora/IPL1-Like Kinase; Aurora-Related Kinase 1; Aurora-A Kinase; EC 2.7.11.1; AURKA; AIRK1; ARK-1; HARK1; AurA; AYK1; IAK1 |
Gene ID | 6790 |
UniProt ID | O14965 |
Target Overview | The protein encoded by this gene is a cell cycle-regulated kinase that appears to be involved in microtubule formation and/or stabilization at the spindle pole during chromosome segregation. The encoded protein is found at the centrosome in interphase cells and at the spindle poles in mitosis. This gene may play a role in tumor development and progression. A processed pseudogene of this gene has been found on chromosome 1, and an unprocessed pseudogene has been found on chromosome 10. Multiple transcript variants encoding the same protein have been found for this gene. |
Chemical Modification | N/A |
Type | DNA |
Length | 20-80 nt |
Affinity (Kd) | 1nM~1μM |
Binding Conditions/Buffer | PBS; buffer system with Serum; other |